AP Chemistry Unit 3.9 Separation of Solubility and Mixtures Chromatography


  • Filtration can be used to separate the insoluble components of a heterogeneous mixture based on differences in particle size but NOT the components of two miscible liquids


  • All methods include a system with two phases: a mobile phase (the solution) and a stationary phase (usually the paper)
  • The substance being analyzed will have a certain amount of attraction to the stationary phase bcuz of differences in polarity
    • If substance is more attracted to mobile phase than paper → it will travel more
      • If it is more attracted to stationary phase rather than mobile phase → it will travel less


  • Difference in InterMFs and thus boiling points between two liquids allow them to be separated by distillation
    • In the vapor above a heated mixture of the two liquids, the compound with the lower BP would dominate → once the vapor cools, the liquid with the lower BP can be collected
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