Henderson-Hasselbalch Equation
- Is only used when dealing with a buffer system
- Is useful for calculating the pH of solutions when the ratio [HA]/[A-] is known
- What if the acid and conjugate base are equal in molarity? pH = pKa
- If you know the pH and pKa, you can know the ratio of [A-]/[HA]
- If the ratio of [A-]/[HA] is < 1 → [HA] > [A-]
- If the ratio of [A-]/[HA] is < 1 → [HA] < [A-]
- If you know the Ka for an acid, can solve for the Kb value of its conjugate base
- Use:
- Use: