IBDP Biology 2025 SL&HL: B3.1 Gas exchange Study Notes

B3.1.1—Gas exchange as a vital function in all organisms 

All organisms respire
Cell respiration releases energy, needed for cell activities movement, beating of heart and breathing movements.

Oxygen + Glucose needed to release energy
Respiration that needs oxygen = aerobic respiration

Gas exchange:   1. Getting oxygen from environment
                                2. Releasing CO2 to environment
Gas exchanges occur by diffusion across cell membrane
Gas Exchange Surface = Surface of the organism dedicated to gas exchanges.

Plants respire, photosynthesize and transpire
Cell respiration releases energy, needed for cell activities
Respiration that needs oxygen = aerobic respiration
Photosynthesis produces organic molecules

Transpiration = loss of water vapour through leaves
Gas exchanges occur by diffusion across cell membrane
Gas Exchange Surface = Surface of the organism dedicated to gas exchanges

If cell size increases, The distance from the centre of cell to its exterior increases , which implies, Exchanges with environment become more challenging

Why the need for a gas exchange system inside large organisms ? 

Small organisms have a large SA/V ratio \(\Rightarrow\) Cells directly in contact with environment
\(\Rightarrow\) Can exchange gases easily with environment


Bigger organisms have a small SA/V ratio \(\Rightarrow\) Cells mostly very far from environment
\(\Rightarrow\) Cannot exchange gases easily with environment \(\Rightarrow\) To exchange enough gases
Oxygen from environment to the respiring cells
CO2 from the respiring cells \(\Rightarrow\) Need a gas exchange system inside the body

B3.1.2—Properties of gas-exchange surfaces

GES used for Respiration in all organisms
Respiration, Photosynthesis and Transpiration in Plants 

Adaptation of mammalian lungs for gas exchange
Thin tissue layer

Thickness of surface = distance that gases have to cover during gas exchange
The thinner the distance, the more efficient the gas exchange \(\Rightarrow\) Gas exchange surfaces are THIN.

 

Adaptation of mammalian lungs for gas exchange
Permeability

B3.1.3—Maintenance of concentration gradients at exchange surfaces in animals 

Adaptation of mammalian lungs for gas exchange
Maintenance of concentration gradients 

Oxygen and carbon dioxide diffuse down their own concentration gradient
The steeper the concentration gradient, the faster the diffusion
Constant ventilation + constant flow of blood maintain these concentration gradients

B3.1.4—Adaptations of mammalian lungs for gas exchange

The respiratory system in humans

 

Internal / External intercostal muscles 

Cartilage in trachea

The Lower Respiratory Tract 

1. Trachea (the windpipe)

  • 16-20 C-shaped rings of cartilage
  • joined by fibroelastic connective tissue
  • Flexible for bending
  • But stays open during breathing

2. Trachea divides into two

  • primary bronchi (bronchus if singular)
  • Enter the lungs

3. Bronchi divide into bronchioles

  • End in alveolar sacs
  • Bronchi and largest bronchioles have cartilage rings too

4. Alveolar sacs are made of alveoli

  • (alveolus if singular)
  • Gas exchanges between air and blood
  • 300 million per human lung

Mucus in trachea and bronchi/bronchioles

Mucus produced by goblet cells
Traps bacteria, spores of fungi, viruses, dust…
Ciliated cells beat their cilia
Move up mucus towards back of the mouth
Mucus swallowed into stomach
pH 2 and HCl kills them all

B3.1.2—Properties of gas-exchange surfaces
B3.1.4—Adaptations of mammalian lungs for gas exchange 

Alveoli have a large surface area to volume ratio

Exchanges of gases between blood and alveoli air

Alveoli have a large surface area in contact with blood vessels for exchanges of gases

600 million of alveoli total 70\(m^2\) = 35 X skin surface = a badminton court

Adaptation of mammalian lungs for gas exchange
Moisture

Land organisms:
Gas exchanges between atmosphere and watery inside of organism
Circulation can only transport liquid and their solutes
Gases from/to atmosphere have to be dissolved before diffusion can occur
Gas exchange surfaces are MOIST
Gas will dissolve in this moistness,
` THEN diffuse in/out

Aquatic organisms:
Gas exchanges between watery environment and watery inside of organism
Gases from/to environment are already dissolved
Diffusion can occur directly

Type I & II Pneumocytes

Type I

• Adapted to carry out gas exchange
• Large total surface area for diffusion
• Make up majority of epithelial cells lining the alveoli
• Flattened cells

Type II

• Secrete a solution containing a surfactant creating a moist surface preventing cell adherence
• Moisture allows oxygen and carbon dioxide to dissolve then diffuse
• Rounded cells

B3.1.5—Ventilation of the lungs

Breathing out = expiration = exhalation

+
Breathing in = inspiration = inhalation
=
Ventilation
i.e. “making wind”
Replacement of air in alveoli to:
– Bring in air rich in oxygen
– Get out air rich in carbon dioxide

\(O_2\) is needed for cell respiration: has to be taken from the air
We breathe in to get oxygen from the air
\(CO_2\) is a metabolic waste produced by cell respiration: has to be gotten rid of
We breathe out to get rid of carbon dioxide

Breathing in = Inspiration = Inhalation

Breathing out = Expiration = Exhalation

A2.2.2—B3.1.6—Measurement of lung volumes 

Application of skills: Students should make measurements to determine tidal volume, vital capacity, and inspiratory and expiratory reserves.

B3.1.7—Adaptations for gas exchange in leaves

• Allow sufficient water to reach the cells in the leaf
• To carry food away to other parts of the plant

  • Stomata (sing. stoma ) = pores in a leaf, mostly on the undersurface
  • Each pore is surrounded by a pair of guard cells 
  • Guard cells can change shape to open or close the stoma

How Guard cells work

  • Guard are the only epidermal cells with chloroplasts
  • In daylight when the stomata opens so \(CO_2\) can enter leaf:
  1. Chloroplasts make sugars (photosynthesis) 
  2. Guard cells actively pump in \(K^{+}\) ions.

B3.1.8—Distribution of tissues in a leaf

Anatomy of a leaf

Cuticle:

• a waxy layer
• prevents water loss from the leaf surface

Upper epidermis:
Protects internal tissues from
1. Mechanical damage
2. And bacterial & fungal invasion
3. Water loss

Columnar cells closely packed together absorb light more efficiently

Opening which allows gases to pass through it to go into or out of the leaf

B3.1.9—Transpiration as a consequence of gas exchange in a leaf 

Factors affecting transpiration in a leaf

Transpiration occurs through the stomata
Stomata open only if there under light
1. Transpiration happens mostly in daylight
2. At night, less water is lost by transpiration
Reduce water loss = Avoid wilting

  • 98% of water entering leaves is lost to the air by transpiration

  • Transpiration only occurs if Ψ air > Ψ air space in leaf
  • Transpiration only occurs if Ψ air > Ψ air space in leaf
    The warmer the air,
    The higher its Ψ
  • Wind moves away the air that has received water vapour from leaf

Hard to measure water vapour loss
Measure water absorbed by roots

  • Xerophytes
    Xero = dryphuton = plant
  • Halophytes
    Halo = saltphuton = plant

B3.1.10—Stomatal density

Application of skills: Students should use micrographs or perform leaf casts to determine stomatal density.

B3.1.11—Adaptations of foetal and adult haemoglobin for the transport of oxygen

In oxygen dissociation curves of haemoglobin,

  • What does a left shift mean?
  • What does a right shift mean?

How can we explain these differences?

B3.1.12—Bohr shift

B3.1.13—Oxygen dissociation curves as a means of representing the affinity of haemoglobin for oxygen at different oxygen concentrations

Red blood cells, haemoglobin and oxygen transport

Red blood cells bind, transport then release oxygen thanks to the protein Hemoglobin

Lungs
Blood needs to take up O2
Hb + O2
gives HbO2 Oxyhaemoglobin
High partial Pressure O2
High affinity of Hb for O2
Maximum take up O2 from air

Respiring tissues
Blood needs to release O2
HbO2 gives Hb + O2 Deoxyhaemoglobin
Low partial Pressure O2
Low affinity of Hb for O2
Maximum release O2 to tissues

Haemoglobin structure

Haemoglobin = Respiratory pigment

Haemoglobin has quaternary structure
Four subunits
Two alpha chains
Two beta chains
Each contains a haeme group that can bind oxygen

Haemoglobin binding oxygen

 

Haemoglobin dissociation curve

Lungs
Hb + O2 gives HbO2 Oxyhaemoglobin
Highest partial Pressure O2
Highest affinity of Hb for O2
Maximum take up O2 from air

Cooperative binding affected by oxygen concentration \(\Rightarrow\) Curve is sigmoid

Respiring tissues
HbO2 gives Hb + O2 Deoxyhaemoglobin
Lowest partial Pressure O2
Lowest affinity of Hb for O2
Maximum release O2 to tissues

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