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AP Statistics 3.6 Selecting an Experimental Design- MCQs - Exam Style Questions

Question

A veterinary student is conducting an experiment to see whether using a certain medicine can reduce symptoms of arthritis in rabbits. Arthritis makes it difficult for rabbits to use one or more limbs. The severity of the arthritis will be based on an evaluation of each rabbit by a veterinarian who does not know whether the rabbit received medicine. Twenty rabbits of different sizes, each with arthritis in one or more limbs, will be randomly assigned to receive medicine or no medicine. The student believes larger rabbits may respond better to the medicine than smaller rabbits will.
Of the following, which experimental design would be best for the veterinary student to use?
(A) A matched pairs design using randomly paired rabbits.
(B) A matched pairs design pairing rabbits of similar size.
(C) A design in which the ten largest rabbits are assigned to receive the medicine and the remaining rabbits are assigned to not receive the medicine.
(D) A design in which the five largest rabbits and the five smallest rabbits are assigned to receive the medicine and the remaining rabbits are assigned to not receive the medicine.
(E) A completely randomized design in which ten rabbits are randomly assigned for each treatment.
▶️ Answer/Explanation
Size is a potential confounder (student believes larger rabbits may respond differently).
Best practice is to control for size by forming matched pairs of similar size, then randomly assign one rabbit in each pair to medicine and the other to no medicine (paired comparison).
This design reduces variability due to size and isolates the treatment effect; the veterinarian’s evaluation is blinded, which helps reduce bias.
(A) random pairing ignores size → poor control of confounding.
(C) and (D) systematically mix size with treatment → confounding the treatment with size.
(E) completely randomized design ignores known size differences → less precise than matched pairs.
Answer: (B)

Question

Suppose a certain scale is not calibrated correctly, and as a result, the mass of any object is displayed as 0.75 kilogram less than its actual mass. What is the correlation between the actual masses of a set of objects and the respective masses of the same set of objects displayed by the scale?
(A) $-1$
(B) $-0.75$
(C) $0$
(D) $0.75$
(E) $1$
▶️ Answer/Explanation
Detailed solution

Let $X$ be the actual mass and $Y$ be the displayed mass.

1. The Calculation:
The relationship is defined by a precise formula:
$Y = X – 0.75$

2. Analysis of the Formula:
– This is the equation of a perfect straight line.
– Because it’s a perfect line, the correlation must be exactly $1$ or $-1$.
– As the actual mass ($X$) increases, the displayed mass ($Y$) also increases. This means the relationship is positive.

A perfect positive relationship has a correlation of 1.
Answer: (E)

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