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AP Statistics 4.5 Carrying Out a Test for a Population Mean or Population Mean Difference- Exam Style Questions - FRQs - New Syllabus

Question

A medical researcher completed a study comparing an omega-3 fatty acids supplement to a placebo in the treatment of irritability in patients with a certain medical condition. Nineteen patients with the medical condition volunteered to participate in the study. The study was conducted using the following weekly schedule.
• Week 1: Each patient took a randomly assigned treatment, omega-3 supplement or placebo.
• Week 2: The patients did not take either the omega-3 supplement or the placebo. This was necessary to reduce the possibility of any carryover effect from the assigned treatment taken during week 1.
• Week 3: Each patient took the treatment, omega-3 supplement or placebo, that they did not take during week 1.
At the end of week 1 and week 3, each patient’s irritability was given a score on a scale of 0 to 10, with 0 representing no irritability and 10 representing the highest level of irritability.
For each patient, the two irritability scores and the difference in their scores (placebo minus omega-3) were recorded. The results are summarized in the table and boxplots.
The researcher claims the omega-3 supplement will decrease the mean irritability score of all patients with the medical condition similar to the volunteers who participated in the study. Is there convincing statistical evidence to support the researcher’s claim at a significance level of \(\alpha=0.05\)? Complete the appropriate inference procedure to support your answer.
 

Most-appropriate topic codes (AP Statistics):

• Topic \(4.4\) — Setting Up a Test for a Population Mean or Population Mean Difference (Entire Question)
• Topic \(4.5\) — Carrying Out a Test for a Population Mean or Population Mean Difference (Entire Question)
▶️ Answer/Explanation

We need to perform a matched-pairs $t$-test for a population mean difference (\(\mu_d = \mu_{\text{placebo}} – \mu_{\text{omega-3}}\)). Our hypotheses are $H_0: \mu_d = 0$ versus $H_a: \mu_d > 0$. The conditions are met: treatments were randomly assigned, and the boxplot of the differences shows no extreme outliers or severe skewness, making the $t$-procedure appropriate for $n=19$.

Calculating the test statistic, we get $t = \frac{1.789 – 0}{2.485 / \sqrt{19}} \approx 3.138$ with $df = 18$. This yields a $p$-value of approximately $0.0028$.

Because the $p$-value ($0.0028$) is less than our significance level (\(\alpha = 0.05\)), we reject the null hypothesis. There is convincing statistical evidence to conclude that the omega-3 supplement decreases the true mean irritability score for patients with this medical condition.

Question

The anterior cruciate ligament (ACL) is one of the ligaments that help stabilize the knee. Surgery is often recommended if the ACL is completely torn, and recovery time from the surgery can be lengthy. A medical center developed a new surgical procedure designed to reduce the average recovery time from the surgery. To test the effectiveness of the new procedure, a study was conducted in which 210 patients needing surgery to repair a torn ACL were randomly assigned to receive either the standard procedure or the new procedure.
(a) Based on the design of the study, would a statistically significant result allow the medical center to conclude that the new procedure causes a reduction in recovery time compared to the standard procedure, for patients similar to those in the study? Explain your answer.
(b) Summary statistics on the recovery times from the surgery are shown in the table.
Do the data provide convincing statistical evidence that those who receive the new procedure will have less recovery time from the surgery, on average, than those who receive the standard procedure, for patients similar to those in the study?

Most-appropriate topic codes (AP Statistics):

• Topic \(1.13\) — Experimental Design (Part \( \mathrm{a} \))
• Topic \(4.5\) — Carrying Out a Test for a Difference of Two Population Means (Part \( \mathrm{b} \))
▶️ Answer/Explanation

(a)
Yes, because the study used random assignment to assign participants to the two treatment groups.
Detailed Solution:
Random assignment creates comparable groups by balancing out potential confounding variables between the standard and new procedure groups.
Because of this design, a statistically significant difference in mean recovery times can indeed be attributed to the causal effect of the surgery type.
The inference applies to the population of patients similar to those who participated in the study.

(b)
Yes, the data provide convincing evidence that the new procedure results in lower average recovery time.
Detailed Solution:
We perform a two-sample $t$-test for a difference in means ($\mu_{standard} – \mu_{new} > 0$).
Calculating the standard error: $SE = \sqrt{\frac{34^2}{110} + \frac{29^2}{100}} = \sqrt{10.509 + 8.41} \approx 4.35$.
Calculating the $t$-statistic: $t = \frac{(217 – 186) – 0}{4.35} \approx 7.13$.
With a $t$-score of approximately $7.13$, the $p$-value is extremely small (virtually $0$), which is less than any standard significance level like $\alpha = 0.05$.
Therefore, we reject the null hypothesis and conclude there is overwhelming statistical evidence that the new procedure reduces recovery time.

Question

Systolic blood pressure is the amount of pressure that blood exerts on blood vessels while the heart is beating. The mean systolic blood pressure for people in the United States is reported to be 122 millimeters of mercury (mmHg) with a standard deviation of 15 mmHg.
The wellness department of a large corporation is investigating whether the mean systolic blood pressure of its employees is greater than the reported national mean. A random sample of 100 employees will be selected, the systolic blood pressure of each employee in the sample will be measured, and the sample mean will be calculated.
Let \(\mu\) represent the mean systolic blood pressure of all employees at the corporation. Consider the following hypotheses.
\(H_0 : \mu = 122\)
\(H_a : \mu > 122\)
(a) Describe a Type II error in the context of the hypothesis test.
(b) Assume that \(\sigma\), the standard deviation of the systolic blood pressure of all employees at the corporation, is \(15\) mmHg. If \(\mu = 122\), the sampling distribution of \(\bar{x}\) for samples of size 100 is approximately normal with a mean of 122 mmHg and a standard deviation of 1.5 mmHg. What values of the sample mean \(\bar{x}\) would represent sufficient evidence to reject the null hypothesis at the significance level of \(\alpha = 0.05\)?
The actual mean systolic blood pressure of all employees at the corporation is 125 mmHg, not the hypothesized value of 122 mmHg, and the standard deviation is 15 mmHg.
(c) Using the actual mean of 125 mmHg and the results from part (b), determine the probability that the null hypothesis will be rejected.
(d) What statistical term is used for the probability found in part (c)?
(e) Suppose the size of the sample of employees to be selected is greater than 100. Would the probability of rejecting the null hypothesis be greater than, less than, or equal to the probability calculated in part (c)? Explain your reasoning.

Most-appropriate topic codes (AP Statistics):

• Topic \(3.11\) — Justifying a Claim Based on a Confidence Interval for the Difference Between Two Population Proportions (Part \( \mathrm{a} \))
• Topic \(4.5\) — Carrying Out a Test for a Population Mean (Part \( \mathrm{b} \))
• Topic \(4.7\) — Constructing a Confidence Interval for the Difference Between Two Population Means (Parts \( \mathrm{c} \), \( \mathrm{d} \), \( \mathrm{e} \))
▶️ Answer/Explanation

(a)
A Type II error occurs when the alternative hypothesis is actually true, but we fail to reject the null hypothesis.
In this context, a Type II error would occur if the true mean systolic blood pressure of all employees is greater than 122 mmHg, but the hypothesis test does not detect this — that is, the null hypothesis (\(H_0 : \mu = 122\)) is not rejected.
In plain terms: the employees really do have higher-than-national-average blood pressure, but the test fails to conclude so.

(b)
Since this is a one-sided (right-tailed) test with known \(\sigma\), we reject \(H_0\) when the test statistic exceeds the critical value \(z^* = 1.645\) at \(\alpha = 0.05\).
The test statistic is \(z = \dfrac{\bar{x} – \mu_0}{\sigma / \sqrt{n}} = \dfrac{\bar{x} – 122}{15/\sqrt{100}} = \dfrac{\bar{x} – 122}{1.5}\).
Setting \(\dfrac{\bar{x} – 122}{1.5} > 1.645\) and solving:
\(\bar{x} – 122 > 1.645 \times 1.5 = 2.4675\)
\(\boxed{\bar{x} > 124.4675 \text{ mmHg}}\)
Any sample mean greater than approximately 124.47 mmHg provides sufficient evidence to reject \(H_0\) at the \(\alpha = 0.05\) level.

(c)
Now the true population mean is \(\mu = 125\) mmHg (with \(\sigma = 15\), \(n = 100\)), so the sampling distribution of \(\bar{x}\) is approximately normal with mean 125 and standard deviation \(\dfrac{15}{\sqrt{100}} = 1.5\).
We want the probability that \(\bar{x}\) falls in the rejection region found in part (b):
\(P(\bar{x} > 124.4675) = P\!\left(z > \dfrac{124.4675 – 125}{1.5}\right) = P(z > -0.355)\ Folk\
\(\boxed{P(z > -0.355) \approx 0.64}\)
There is approximately a 64% probability that the null hypothesis will be rejected when the true mean is 125 mmHg.

(d)
The probability found in part (c) — the probability of correctly rejecting a false null hypothesis — is called the power of the test.
\(\boxed{\text{Power of the test} \approx 0.64}\)

(e)
The probability of rejecting \(H_0\) would be greater than 0.64 if the sample size is larger than 100.
A larger sample size \(n\) reduces the standard error of \(\bar{x}\): \(\sigma_{\bar{x}} = \dfrac{\sigma}{\sqrt{n}}\), so the sampling distribution becomes narrower.
This means the critical value \(\bar{x}^* = \mu_0 + z^* \cdot \dfrac{\sigma}{\sqrt{n}}\) would be smaller (closer to 122), lowering the threshold needed to reject \(H_0\).
With a lower rejection threshold, it becomes more likely that \(\bar{x}\) exceeds that threshold when the true mean is 125 mmHg — so the power of the test increases.
\(\boxed{\text{Probability of rejecting } H_0 \text{ would be greater than 0.64.}}\)

Question

A researcher conducted a study to investigate whether local car dealers tend to charge women more than men for the same car model. Using information from the county tax collector’s records, the researcher randomly selected one man and one woman from among everyone who had purchased the same model of an identically equipped car from the same dealer. The process was repeated for a total of 8 randomly selected car models.
The purchase prices and the differences (woman − man) are shown in the table below. Summary statistics are also shown.
 
Dotplots of the data and the differences are shown below.
Do the data provide convincing evidence that, on average, women pay more than men in the county for the same car model?

Most-appropriate topic codes (AP Statistics):

• Topic \(4.4\) — Setting Up a Test for a Population Mean Difference (full question)
• Topic \(4.5\) — Carrying Out a Test for a Population Mean Difference (full question)
▶️ Answer/Explanation

Step 1: State the hypotheses.
Let \(\mu_{\text{diff}}\) be the population mean difference in purchase price (woman − man) for identically equipped cars of the same model sold by the same dealer in the county.
\(H_0 : \mu_{\text{diff}} = 0\) (on average, women and men pay the same)
\(H_a : \mu_{\text{diff}} > 0\) (on average, women pay more than men)

Step 2: Identify the procedure and check conditions.
Since each pair consists of one man and one woman buying the same car model from the same dealer, the data are paired. The appropriate procedure is a paired \(t\)-test.
Random: The 8 car models were randomly selected and within each model, one man and one woman were randomly selected. The random condition is met.
Normal/Large Sample: The sample size \(n = 8\) is small, so we cannot rely on the Central Limit Theorem. The dotplot of the differences shows a roughly symmetric distribution with no strong skewness or outliers, so it is reasonable to assume the population of differences is approximately normally distributed. The normal condition is considered met.

Step 3: Calculate the test statistic and \(p\)-value.
From the summary statistics for the differences: \(\bar{x}_d = 585\), \(s_d = 530.71\), \(n = 8\).
The test statistic is:
\(t = \dfrac{\bar{x}_d – 0}{\dfrac{s_d}{\sqrt{n}}} = \dfrac{585 – 0}{\dfrac{530.71}{\sqrt{8}}} = \dfrac{585}{187.63} \approx 3.12\)
Degrees of freedom: \(df = n – 1 = 8 – 1 = 7\)
The \(p\)-value for a one-sided \(t\)-test with \(t \approx 3.12\) and \(df = 7\) is:
\(p\text{-value} \approx 0.008\)

Step 4: State the conclusion in context.
Since the \(p\)-value of \(0.008\) is less than \(\alpha = 0.05\), we reject \(H_0\). The data provide convincing evidence that, on average, women pay more than men in the county for the same car model.

Question

A bottle-filling machine is set to dispense 12.1 fluid ounces into juice bottles. To ensure that the machine is filling accurately, every hour a worker randomly selects four bottles filled by the machine during the past hour and measures the contents. If there is convincing evidence that the mean amount of juice dispensed is different from 12.1 ounces or if there is convincing evidence that the standard deviation is greater than 0.05 ounce, the machine is shut down for recalibration. It can be assumed that the amount of juice that is dispensed into bottles is normally distributed.
During one hour, the mean number of fluid ounces of four randomly selected bottles was 12.05 and the standard deviation was 0.085 ounce.
(a) Perform a test of significance to determine whether the mean amount of juice dispensed is different from 12.1 fluid ounces. Assume the conditions for inference are met.
(b) To determine whether this sample of four bottles provides convincing evidence that the standard deviation of the amount of juice dispensed is greater than 0.05 ounce, a simulation study was performed. In the simulation study, 300 samples, each of size 4, were randomly generated from a normal population with a mean of 12.1 and a standard deviation of 0.05. The sample standard deviation was computed for each of the 300 samples. The dotplot below displays the values of the sample standard deviations.
Use the results of this simulation study to explain why you think the sample provides or does not provide evidence that the standard deviation of the juice dispensed exceeds 0.05 fluid ounce.

Most-appropriate topic codes (AP Statistics):

• Topic \(4.4\) — Setting Up a Test for a Population Mean or Population Mean Difference (Part \(\mathrm{a}\): hypotheses and test selection)
• Topic \(4.5\) — Carrying Out a Test for a Population Mean or Population Mean Difference (Part \(\mathrm{a}\): test statistic, \(p\)-value, and conclusion)
• Topic \(2.3\) — Estimating Probabilities Using Simulation (Part \(\mathrm{b}\): simulation-based estimation of a \(p\)-value)
• Topic \(3.6\) — p-Values (Part \(\mathrm{b}\): interpreting simulated \(p\)-value evidence)
▶️ Answer/Explanation

(a)
Let \(\mu\) = the true mean number of fluid ounces dispensed into all juice bottles filled by the machine in the past hour.
Step 1 — Hypotheses:
\(H_0: \mu = 12.1\)
\(H_a: \mu \neq 12.1\)

Step 2 — Test: One-sample \(t\)-test for a mean (conditions are given as met; population standard deviation is unknown).
\(t = \frac{\bar{x} – \mu_0}{s/\sqrt{n}}\)

Step 3 — Mechanics:
Given: \(\bar{x} = 12.05\), \(s = 0.085\), \(n = 4\), \(\mu_0 = 12.1\)
\(t = \frac{12.05 – 12.1}{0.085/\sqrt{4}} = \frac{-0.05}{0.0425} \approx -1.176\)
Degrees of freedom: \(df = n – 1 = 3\)
Two-sided \(p\)-value:
\(p\text{-value} = 2 \cdot P(T_3 < -1.176) \approx 0.324\)

Step 4 — Conclusion:
Since the \(p\)-value of \(0.324\) is much larger than any reasonable significance level (such as \(\alpha = 0.05\)), we fail to reject \(H_0\).
There is not sufficient evidence to conclude that the mean amount of juice being dispensed is different from \(12.1\) fluid ounces. The machine does not need to be shut down on the basis of the mean.

(b)

In the simulation, 300 samples of size 4 were drawn from a normal population with \(\sigma = 0.05\). The sample standard deviation of \(s = 0.085\) from our actual data falls well out in the right tail of the dotplot.
Counting the dots at or beyond \(0.085\) in the dotplot, only about 12 out of 300 simulated values are as large or larger than \(0.085\).
This gives an estimated (simulated) \(p\)-value of:
\(\hat{p}\text{-value} = \frac{12}{300} = 0.04\)
Since this simulated \(p\)-value of \(0.04\) is less than \(\alpha = 0.05\), the sample does provide convincing evidence that the true standard deviation of the juice dispensed exceeds \(0.05\) fluid ounce. The machine should be shut down for recalibration.

Question

Administrators in a large school district wanted to determine whether students who attended a new magnet school for one year achieved greater improvement in science test performance than students who did not attend the magnet school. Knowing that more parents would want to enroll their children in the magnet school than there was space available for those children, the district administrators decided to conduct a lottery of all families who expressed interest in participating. In their data analysis, the administrators would then compare the change in test scores of those children who were selected to attend the magnet school with the change in test scores of those who applied to attend the magnet school but who were not selected.
The tables below show the scores on the same science pretest and the same science posttest for 20 students. Of the 20 students, 8 were randomly selected from the magnet school and 12 were randomly selected from those who applied to attend the magnet school but who were not selected and then attended their original school.
(a) Perform a test to determine whether students who attend the magnet school demonstrate a significantly higher mean difference in test scores \((\text{Posttest} – \text{Pretest})\) than students who applied to attend the magnet school but who were not selected and then attended their original school.
Administrators were also interested in using pretest scores on this test as a predictor of posttest scores on the test. The following computer output contains the results from separate regression analyses on the magnet school scores and on the original school scores. The accompanying graph displays the data and separate regression lines for the magnet and original schools.

(b)

(i) State the equation of the regression line for the magnet school and interpret its slope in the context of the question.
(ii) State the equation of the regression line for the original school and interpret its slope in the context of the question.
(c) To determine whether there is a significant correlation between pretest score and posttest score, a test of the following hypotheses will be performed.
\(H_0\): There is no correlation between pretest score and posttest score (true slope \(= 0\))
versus
\(H_a\): There is a correlation between pretest score and posttest score (true slope \(\neq 0\))
(i) Using the regression output, state the \(p\)-value and conclusion for this test at the magnet school. Assume the conditions for inference have been met.
(ii) Using the regression output, state the \(p\)-value and conclusion for this test at the original school. Assume the conditions for inference have been met.
(d) What additional information do the regression analyses give you about student performance on the science test at the two schools beyond the comparison of mean differences in part (a)?

Most-appropriate topic codes (AP Statistics):

• Topic 4.4 — Setting Up a Test for a Population Mean or Population Mean Difference (Part \(\mathrm{a}\))
• Topic 4.5 — Carrying Out a Test for a Population Mean or Population Mean Difference (Part \(\mathrm{a}\))
• Topic 5.3 — Linear Regression Models (Part \(\mathrm{b}\))
• Topic 5.2 — Correlation (Part \(\mathrm{c}\))
• Topic 5.5 — Least-Squares Regression (Parts \(\mathrm{b}\), \(\mathrm{c}\), \(\mathrm{d}\))
▶️ Answer/Explanation

(a)

Step 1 — Hypotheses
Let \(\mu_{\text{DiffM}}\) = the mean difference (posttest \(-\) pretest) for all students at the magnet school, and \(\mu_{\text{DiffO}}\) = the mean difference for all students who applied but were not selected and attended their original school.
\(H_0: \mu_{\text{DiffM}} = \mu_{\text{DiffO}}\)
\(H_a: \mu_{\text{DiffM}} > \mu_{\text{DiffO}}\)

Step 2 — Test and Conditions

We use a two-sample \(t\)-test for the difference of two means:
\(t = \dfrac{\bar{x}_M – \bar{x}_O}{\sqrt{\dfrac{s_M^2}{n_M} + \dfrac{s_O^2}{n_O}}}\)

  1. We need to assume randomness of the sampling used. It was stated in the stem that the students from the two different schools were randomly selected.
  2. We need to check the assumption that the distributions of differences (posttest – pretest) for each of the two schools are normally distributed. Based on histograms and boxplots of these differences, there are no outliers or extreme skewness. Because these graphs reveal no obvious departures from normality, it appears reasonable to proceed with the t-test.

Step 3 — Test Statistic and \(p\)-value
\(t = \dfrac{11.750 – 3.000}{\sqrt{\dfrac{(9.407)^2}{8} + \dfrac{(3.977)^2}{12}}} = \dfrac{8.750}{\sqrt{11.062 + 1.318}} = \dfrac{8.750}{\sqrt{12.380}} = \dfrac{8.750}{3.518} \approx 2.487\)
\(df \approx 8.69\), \(\quad p\text{-value} \approx 0.0177\)

Step 4 — Conclusion
Since \(p = 0.0177 < \alpha = 0.05\), we reject \(H_0\). There is convincing evidence that students who attend the magnet school have a higher mean improvement in science test scores than students who attended their original school.

(b)(i)

The regression equation for the magnet school is:
\(\hat{y} = 73.27 + 0.1811x\)
where \(x\) is the pretest score and \(\hat{y}\) is the predicted posttest score. The slope of \(0.1811\) means that for each additional point scored on the pretest by a magnet school student, the posttest score is predicted to increase by \(0.1811\) points, on average. The slope is positive but very close to zero, suggesting that pretest performance has almost no predictive power for posttest performance at the magnet school.

(b)(ii)

The regression equation for the original school is:
\(\hat{y} = 9.24 + 0.9204x\)
where \(x\) is the pretest score and \(\hat{y}\) is the predicted posttest score. The slope of \(0.9204\) means that for each additional point scored on the pretest by an original school student, the posttest score is predicted to increase by approximately \(0.9204\) points, on average — a nearly one-for-one relationship.

(c)(i) — Magnet School
From the regression output, the test statistic is \(t = 0.40\) with \(p\text{-value} = 0.706\).
Since \(0.706 > 0.05\), we fail to reject \(H_0\). There is insufficient evidence to conclude that there is a significant correlation between pretest score and posttest score at the magnet school. Pretest score is not a useful linear predictor of posttest score for magnet school students.

(c)(ii) — Original School

From the regression output, the test statistic is \(t = 6.09\) with \(p\text{-value} = 0.000\).
Since \(0.000 < 0.05\), we reject \(H_0\). There is strong evidence of a significant correlation between pretest score and posttest score at the original school. Pretest score is a very strong linear predictor of posttest score for original school students.

(d)

The two-sample \(t\)-test in part (a) told us only that the magnet school group had a higher average improvement — but it didn’t explain who benefited or by how much depending on their initial ability. The regression analyses reveal something much more interesting:
• At the magnet school, the slope is nearly zero (\(0.1811\)), and \(R^2 = 2.5\%\) — this means students score high on the posttest regardless of how they did on the pretest. A student who entered the magnet school with a low pretest score of 64 scored 89 on the posttest (an improvement of 25 points), while a student with a higher pretest score of 86 actually dropped 2 points. The magnet school appears to level the playing field and disproportionately benefits students who start with lower ability.
• At the original school, the slope is close to 1 (\(0.9204\)) and \(R^2 = 78.8\%\) — students essentially maintained their relative ranking, with high pretest scorers also achieving high posttest scores. There is very little “boost” effect for any student regardless of their starting point.
In short, the regression analyses reveal that the magnet school benefits students with low pretest scores the most, while the original school produces predictable but modest gains proportional to where students started.

Question

The nerves that supply sensation to the front portion of a person’s foot run between the long bones of the foot. Tight-fitting shoes can squeeze these nerves between the bones, causing pain when the nerves swell. This condition is called Morton’s neuroma. Because most people have a dominant foot, muscular development is not the same in both feet. People who have Morton’s neuroma may have the condition in only one foot or they may have it in both feet.
Investigators selected a random sample of 12 adult female patients with Morton’s neuroma to study this disease further. The data below are measurements of nerve swelling as recorded by a physician. A value of 1.0 is considered “normal,” and 2.0 is considered extreme swelling. The population distribution of the swelling measurements is approximately normal for adult females who have Morton’s neuroma.
(a) A scatterplot of the ordered pairs (swelling in left foot, swelling in right foot), is shown below.
The scatterplot suggests there are two distinct groups of patients. Patients within each group share a common trait. Use the scatterplot above and the table to determine the common trait and explain how this trait differs for the two groups.
(b) A scatterplot of the ordered pairs (swelling in dominant foot, swelling in nondominant foot), is shown below.
What conclusion can be drawn from this scatterplot that is not apparent from the scatterplot in part (a)?
(c) Can you conclude that there is a difference between the mean swelling in the dominant foot and the mean swelling in the nondominant foot for adult females who have Morton’s neuroma in at least one foot? Give a statistical justification to support your answer.
(For easy reference, the table of data from above also appears at the bottom of this question.)
(d) The nerve swelling measurement is used to indicate whether a foot has Morton’s neuroma. Use the 24 measurements of nerve swelling to suggest a criterion for diagnosing Morton’s neuroma. Justify your suggestion graphically.
(For easy reference, the table of data from above also appears below.)

Most-appropriate topic codes (AP Statistics):

• Topic 5.1 — Graphical Representations Between Two Quantitative Variables (Parts \(\mathrm{a}\), \(\mathrm{b}\))
• Topic 4.4 — Setting Up a Test for a Population Mean or Population Mean Difference (Part \(\mathrm{c}\))
• Topic 4.5 — Carrying Out a Test for a Population Mean or Population Mean Difference (Part \(\mathrm{c}\))
• Topic 1.5 — Graphical Representations for One Quantitative Variable (Part \(\mathrm{d}\))
• Topic 1.9 — Comparisons of the Distributions for One Quantitative Variable (Part \(\mathrm{d}\))
▶️ Answer/Explanation

(a)

The trait that distinguishes the two groups in the scatterplot is the dominant foot (left or right). All the points in the upper-left cluster represent patients whose dominant foot is the right foot, while all the points in the lower-right cluster represent patients whose dominant foot is the left foot. The dominant foot type is the common trait, and it differs between the two groups.

(b)

Two conclusions become clear from this scatterplot that were not visible before:
First, there is a positive linear relationship between swelling in the dominant foot and swelling in the nondominant foot — as swelling in the dominant foot increases, swelling in the nondominant foot tends to increase as well.
Second, and importantly, every single point lies below the line \(y = x\), which means swelling in the dominant foot is consistently greater than swelling in the nondominant foot for all patients in the sample. This pattern across both groups combined is something you simply could not see in the left-foot vs. right-foot scatterplot from part (a).

(c)

We perform a matched-pairs \(t\)-test on the differences \(d_i = \text{(dominant swelling)} – \text{(nondominant swelling)}\).
The 12 differences are:
\(0.30,\ 0.30,\ 0.45,\ 0.15,\ 0.30,\ 0.35,\ 0.25,\ 0.35,\ 0.20,\ 0.25,\ 0.40,\ 0.15\)
State hypotheses (where \(\mu_d\) is the mean difference, dominant minus nondominant):
\(H_0: \mu_d = 0\)
\(H_a: \mu_d \neq 0\)
Check conditions:
1. We are told a random sample was selected from the population of adult females with Morton’s neuroma.
2. A dotplot of the differences shows a roughly symmetric, unimodal distribution with no outliers — it is reasonable to treat the population of differences as approximately normal.
Compute the test statistic:
\(\bar{x}_d = 0.2875, \quad s_d = 0.0932, \quad n = 12, \quad df = 11\)
\(t = \dfrac{\bar{x}_d – 0}{\dfrac{s_d}{\sqrt{n}}} = \dfrac{0.2875 – 0}{\dfrac{0.0932}{\sqrt{12}}} = 10.68\)
\(p\text{-value} \approx 0.0000004 \approx 0\)
Since the \(p\)-value is essentially \(0\), which is far less than any reasonable significance level \(\alpha\), we reject \(H_0\). There is very convincing statistical evidence that the mean swelling in the dominant foot is different from (and specifically greater than) the mean swelling in the nondominant foot for adult females who have Morton’s neuroma in at least one foot.

(d)

To suggest a diagnostic criterion, we separate all 24 swelling measurements into two groups: the 17 foot measurements from feet that have Morton’s neuroma and the 7 foot measurements from feet that do not have Morton’s neuroma. A stacked dotplot of the two groups is shown below:

The dotplot makes it visually clear that all 7 feet without Morton’s neuroma have swelling measurements of \(1.40\) or below, while the feet with Morton’s neuroma have swelling values of \(1.40\) and above (with the measurements extending up to \(1.85\)). Based on this graphical display, a reasonable diagnostic criterion is:
\(\boxed{\text{Swelling measurement} \geq 1.4 \Rightarrow \text{diagnose Morton’s neuroma}}\)
A cutoff of approximately \(1.4\) or higher serves as a sensible threshold for diagnosing Morton’s neuroma, since it cleanly separates the feet with and without the condition in this dataset.

Question

Investigators at the U.S. Department of Agriculture wished to compare methods of determining the level of E. coli bacteria contamination in beef. Two different methods (A and B) of determining the level of contamination were used on each of ten randomly selected specimens of a certain type of beef. The data obtained, in millimicrobes/liter of ground beef, for each of the methods are shown in the table below.
Is there a significant difference in the mean amount of E. coli bacteria detected by the two methods for this type of beef? Provide a statistical justification to support your answer.

Most-appropriate topic codes (AP Statistics):

• Topic 4.4 — Setting Up a Test for a Population Mean or Population Mean Difference (Hypotheses and Conditions)
• Topic 4.5 — Carrying Out a Test for a Population Mean or Population Mean Difference (Test Mechanics and Conclusion)
• Topic 1.5 — Graphical Representations for One Quantitative Variable (Checking the Distribution of Differences)
▶️ Answer/Explanation

We conduct a paired \(t\)-test for the mean difference in the level of E. coli bacteria contamination detected by the two methods.

Step 1 — Hypotheses
Let \(\mu_d\) be the population mean difference in E. coli contamination levels (Method A \(-\) Method B).
\(H_0: \mu_d = 0\) (no difference in mean contamination detected by the two methods)
\(H_a: \mu_d \neq 0\) (there is a difference in mean contamination detected by the two methods)

Step 2 — Identify Test and Check Conditions
We use a paired \(t\)-test with test statistic:
\(t = \dfrac{\bar{x}_d – 0}{s_d / \sqrt{n_d}}\)
First, compute the differences \(d_i = A_i – B_i\) for each specimen:
\(-0.3,\quad 0.5,\quad 0.3,\quad 0.6,\quad 0.8,\quad 0.7,\quad 1.2,\quad 0.2,\quad -0.1,\quad -1.0\)

Condition 1 — Independence: The 10 specimens were randomly selected, so it is reasonable to assume the 10 pairs of measurements are independent of one another.
Condition 2 — Normality of Differences: With only \(n = 10\) differences, we check a histogram or boxplot of the differences. The histogram of the differences \((A – B)\) is roughly symmetric with no apparent outliers, so it is reasonable to assume the population distribution of differences is approximately normal.

Step 3 — Mechanics
From the differences:
\(\bar{x}_d = 0.29, \qquad s_d = 0.6297, \qquad n = 10\)
\(t = \dfrac{0.29 – 0}{0.6297/\sqrt{10}} = \dfrac{0.29}{0.1991} \approx 1.456\)
\(\text{degrees of freedom} = n – 1 = 9\)
\(p\text{-value} = 2 \times P(t_9 > 1.456) \approx 0.1793\)

Step 4 — Conclusion
Since the \(p\)-value of \(0.1793\) is greater than \(\alpha = 0.05\), we fail to reject \(H_0\).
We do not have statistically significant evidence to conclude that there is a difference in the mean amount of E. coli bacteria detected by the two methods for this type of beef.
\(\boxed{p\text{-value} = 0.1793 > 0.05 \Rightarrow \text{Fail to reject } H_0; \text{ no significant difference between the two methods.}}\)

Question

A manufacturer of thermostats is concerned that the readings of its thermostats have become less reliable (more variable). In the past, the variance has been \(1.52\) degrees Fahrenheit (F) squared. A random sample of \(10\) recently manufactured thermostats was selected and placed in a room that was maintained at \(68^\circ\text{F}\). The readings for those 10 thermostats are given in the table below.
(a) State the null and alternative hypotheses that the manufacturer is interested in testing.
It can be shown that if the population of thermostat temperatures is normally distributed, the sampling distribution of \(\dfrac{(n-1)s^2}{\sigma^2}\) follows a chi-square distribution with \(n-1\) degrees of freedom.
(b) Calculate the value of \(\dfrac{(n-1)s^2}{1.52}\) for these data.
(c) Assume that the population of thermostat temperatures follows a normal distribution. Use the test statistic \(\dfrac{(n-1)s^2}{1.52}\) from part (b) and the chi-square distribution to test the hypotheses in part (a).
(d) For the test conducted in part (c), what is the smallest value of the test statistic that would have led to the rejection of the null hypothesis at the 5 percent significance level?
Mark this value of the test statistic on the graph of the chi-square distribution below. Indicate the region that contains all of the values that would have led to the rejection of the null hypothesis.

(e) Using simulation, 1,000 samples, each of size 10, were randomly generated from 3 populations with different variances. Each population was normally distributed with mean 68 and variance greater than 1.52. The histograms below show the simulated sampling distribution of \(\dfrac{(n-1)s^2}{1.52}\) for each population.
Mark the region identified in part (d) on each of the histograms below.

(f) Based on the regions that you marked in part (e), identify the simulated sampling distribution that corresponds to the population with the largest variance. Then identify the simulated sampling distribution that corresponds to the population with the smallest variance. Justify your choices.

Most-appropriate topic codes (AP Statistics):

• Topic 4.4 — Setting Up a Test for a Population Mean or Population Mean Difference (Part \(\mathrm{a}\))
• Topic 4.5 — Carrying Out a Test for a Population Mean or Population Mean Difference (Parts \(\mathrm{b}\), \(\mathrm{c}\), \(\mathrm{d}\))
• Topic 2.12 — Sampling Distributions and the Central Limit Theorem (Parts \(\mathrm{e}\), \(\mathrm{f}\))
▶️ Answer/Explanation

(a)

Let \(\sigma^2\) denote the true population variance of the readings of recently manufactured thermostats (in degrees Fahrenheit squared).
\(H_0: \sigma^2 = 1.52 \qquad \text{(variance has not changed)}\)
\(H_a: \sigma^2 > 1.52 \qquad \text{(recently produced thermostats are more variable)}\)

(b)

First, compute the sample standard deviation from the 10 readings:
\(s^2 = 2.0383 \implies s = 1.4277\)
Then compute the test statistic:
\(\chi^2 = \frac{(n-1)s^2}{1.52} = \frac{9 \times 2.0383}{1.52} = \frac{18.345}{1.52}\)
\(\boxed{\chi^2 \approx 12.069}\)

(c)

Under \(H_0\), the test statistic follows a \(\chi^2\) distribution with \(n – 1 = 9\) degrees of freedom.
The \(p\)-value is the probability of obtaining a test statistic as large as or larger than the observed value:
\(p\text{-value} = P\!\left(\chi^2_9 \geq 12.069\right) \approx 0.2094\)
(From the table: \(0.20 < p\text{-value} < 0.25\))
Since the \(p\)-value \(\approx 0.2094 > 0.05\), we fail to reject \(H_0\). There is not statistically significant evidence at the \(\alpha = 0.05\) level that the recently manufactured thermostats have become more variable than in the past.
\(\boxed{\text{Fail to reject } H_0;\ p\text{-value} \approx 0.209}\)

(d)

The smallest value of the test statistic that leads to rejection of \(H_0\) at the 5% significance level is the 95th percentile of the \(\chi^2\) distribution with 9 degrees of freedom:
\(\boxed{\chi^2_{0.05,\,9} = 16.92}\)
The rejection region consists of all chi-square values greater than or equal to \(16.92\), which corresponds to the shaded right tail of the \(\chi^2_9\) curve (as marked on the graph above).

(e)

The rejection region — all simulated values to the right of \(16.92\) — should be marked on each of the three histograms (Histogram I, Histogram II, and Histogram III) as indicated by the dashed vertical lines in the diagrams above.

(f)

Largest variance → Histogram III. A population with a larger variance will tend to produce larger sample variances \(s^2\), and hence larger values of the test statistic \(\frac{(n-1)s^2}{1.52}\). Histogram III has the greatest proportion of simulated values falling to the right of \(16.92\) — meaning it has the highest probability of correctly rejecting \(H_0\) — so it corresponds to the population with the largest variance.
Smallest variance → Histogram II. Histogram II has its simulated values concentrated most tightly at smaller values, with the smallest proportion of values exceeding \(16.92\). This means it has the lowest probability of rejecting \(H_0\), consistent with coming from the population whose variance is smallest (and closest to \(1.52\) among the three).
\(\boxed{\text{Largest variance: Histogram III} \qquad \text{Smallest variance: Histogram II}}\)

Question

The developers of a training program designed to improve manual dexterity claim that people who complete the 6-week program will increase their manual dexterity. A random sample of 12 people enrolled in the training program was selected. A measure of each person’s dexterity on a scale from 1 (lowest) to 9 (highest) was recorded just before the start of and just after the completion of the 6-week program. The data are shown in the table below.
Can one conclude that the mean manual dexterity for people who have completed the 6-week training program has significantly increased? Support your conclusion with appropriate statistical evidence.

Most-appropriate topic codes (AP Statistics):

• Topic 4.4 — Setting Up a Test for a Population Mean or Population Mean Difference (Hypotheses and Conditions)
• Topic 4.5 — Carrying Out a Test for a Population Mean or Population Mean Difference (Test Statistic, \(p\)-value, and Conclusion)
▶️ Answer/Explanation

Step 1: State the hypotheses.
Let \(\mu_D\) denote the mean difference (after \(-\) before) in dexterity scores for the population of individuals enrolled in the program.
\(H_0: \mu_D = 0\)
\(H_a: \mu_D > 0\)

Step 2: Identify the correct test and check conditions.
Since the data consist of before-and-after measurements on the same individuals, we use a one-sample paired \(t\)-test on the differences \(d_i = \text{after}_i – \text{before}_i\).
The individual differences are: \(1.1,\ 0.5,\ 0.6,\ 0,\ 0.7,\ 0.5,\ 0.5,\ -0.1,\ -0.1,\ 0.5,\ 0.3,\ 0\)
Conditions:
1. Random sample: The problem states that the 12 people are a random sample from the population enrolled in the program.
2. Approximate normality: With only \(n = 12\) observations, we check the distribution of differences. A dotplot or histogram of the differences shows no strong skewness or outliers, so it is reasonable to assume the differences are approximately normally distributed.

Step 3: Compute the test statistic and \(p\)-value.
From the differences, we compute:
\(\bar{d} = \frac{85.6 – 81.1}{12} = \frac{4.5}{12} = 0.375\)
\(s_d = 0.367\)
\(\text{Degrees of freedom} = n – 1 = 12 – 1 = 11\)
\(t = \frac{\bar{d} – 0}{s_d / \sqrt{n}} = \frac{0.375 – 0}{0.367 / \sqrt{12}} = \frac{0.375}{0.1059} = 3.54\)
\(p\text{-value} = P(t_{11} > 3.54) \approx 0.002\)

Step 4: State the conclusion in context.
Since the \(p\)-value (\(\approx 0.002\)) is less than any common significance level such as \(\alpha = 0.05\), we reject \(H_0\).
There is sufficient, statistically significant evidence to conclude that, on average, people who completed the 6-week training program have meaningfully increased their manual dexterity.
\(\boxed{t = 3.54,\quad p\text{-value} \approx 0.002 \implies \text{Reject } H_0 \text{ — mean dexterity has significantly increased}}\)

Question

Regulations require that product labels on containers of food that are available for sale to the public accurately state the amount of food in those containers. Specifically, if milk containers are labeled to have 128 fluid ounces and the mean number of fluid ounces of milk in the containers is at least 128, the milk processor is considered to be in compliance with the regulations. The filling machines can be set to the labeled amount. Variability in the filling process causes the actual contents of milk containers to be normally distributed. A random sample of 12 containers of milk was drawn from the milk processing line in a plant, and the amount of milk in each container was recorded.
(a) The sample mean and standard deviation of this sample of 12 containers of milk were 127.2 ounces and 2.1 ounces, respectively. Is there sufficient evidence to conclude that the packaging plant is not in compliance with the regulations? Provide statistical justification for your answer.
Inspectors decide to study a particular filling machine within this plant further. For this machine, the amount of milk in the containers has a mean of 128.0 fluid ounces and a standard deviation of 2.0 fluid ounces.
(b) What is the probability that a randomly selected container filled by this machine contains at least 125 fluid ounces?
(c) An inspector will randomly select 12 containers filled by this machine and record the amount of milk in each. What is the probability that the minimum (smallest amount of milk) recorded in the 12 containers will be at least 125 fluid ounces? (Note: In order for the minimum to be at least 125 fluid ounces, each of the 12 containers must contain at least 125 fluid ounces.)
An analyst wants to use simulation to investigate the sampling distribution of the minimum. This analyst randomly generates 150 samples, each consisting of 12 observations, from a normal distribution with mean 128 and standard deviation 2 and finds the minimum for each sample. The 150 minimums (sorted from smallest to largest) are shown in the table below.
SampleMinimumSampleMinimumSampleMinimum
1121.4551124.28101125.25
2122.5152124.29102125.31
3122.5353124.30103125.36
4122.7254124.31104125.38
5122.7555124.34105125.40
6122.8956124.36106125.42
7122.9357124.37107125.48
8122.9958124.37108125.49
9123.0459124.39109125.50
10123.0860124.39110125.52
11123.0961124.41111125.54
12123.1062124.44112125.56
13123.3163124.53113125.61
14123.3464124.53114125.67
15123.3965124.54115125.72
16123.4066124.55116125.76
17123.4167124.55117125.77
18123.4168124.55118125.78
19123.4669124.55119125.79
20123.4970124.58120125.84
21123.5171124.67121125.87
22123.5772124.69122125.87
23123.5873124.73123125.90
24123.5974124.77124125.90
25123.6075124.78125125.93
26123.6676124.78126125.93
27123.6777124.80127125.93
28123.7278124.80128125.94
29123.7579124.81129125.98
30123.7780124.85130126.00
31123.7881124.91131126.03
32123.8482124.92132126.05
33123.9183124.92133126.05
34123.9384124.96134126.06
35123.9585125.00135126.09
36123.9586125.01136126.15
37123.9887125.02137126.15
38123.9988125.02138126.16
39124.0589125.03139126.19
40124.0590125.04140126.19
41124.0691125.05141126.25
42124.1292125.07142126.26
43124.1493125.08143126.33
44124.1594125.09144126.35
45124.1695125.14145126.45
46124.1996125.18146126.50
47124.2397125.21147126.57
48124.2798125.21148126.62
49124.2899125.22149126.64
50124.28100125.25150126.95
(d) Use the simulation results to estimate the probability that was requested in part (c) and compare this estimate with the theoretical value you calculated.

Most-appropriate topic codes (AP Statistics):

• Topic 4.4 — Setting Up a Test for a Population Mean or Population Mean Difference (Part a)
• Topic 4.5 — Carrying Out a Test for a Population Mean or Population Mean Difference (Part a)
• Topic 2.11 — The Normal Distribution (Parts b, c)
• Topic 2.3 — Estimating Probabilities Using Simulation (Part d)
▶️ Answer/Explanation

(a)

Step 1 — State the hypotheses:
\( H_0: \mu = 128 \text{ fl oz} \quad \text{vs.} \quad H_a: \mu < 128 \text{ fl oz} \)
where \(\mu\) is the true mean amount of milk in containers from this plant.
We test whether the mean is below 128 fl oz, since that would indicate non-compliance.
Step 2 — Identify the procedure and check conditions:
Use a one-sample \(t\)-test for a mean:
\( t = \frac{\bar{x} – \mu_0}{s/\sqrt{n}} \)
The problem states the filling process produces a normal distribution, so the normality condition is satisfied.
The containers were randomly sampled, so independence holds.
Step 3 — Compute the test statistic and p-value:
With \(\bar{x} = 127.2\), \(\mu_0 = 128\), \(s = 2.1\), \(n = 12\):
\( t = \frac{127.2 – 128}{2.1/\sqrt{12}} = \frac{-0.8}{0.6062} \approx -1.319 \)
Degrees of freedom: \(df = n – 1 = 11\).
For a one-tailed test with \(t = -1.319\) and \(df = 11\):
\( p\text{-value} = P(T_{11} < -1.319) \approx 0.107 \)
Step 4 — State the conclusion in context:
Since the p-value of \(0.107\) is greater than any reasonable significance level (e.g., \(\alpha = 0.05\)), we fail to reject \(H_0\). There is not sufficient evidence to conclude that the plant is out of compliance. The sample mean of 127.2 fl oz is below 128, but the difference is small enough that it could plausibly be due to random sampling variability alone.

(b)

Let \(X\) be the amount of milk in a randomly selected container, where \(X \sim N(128.0,\ 2.0)\). We want \(P(X \geq 125)\).
Standardize by converting to a \(z\)-score: \( z = \frac{125 – 128}{2} = \frac{-3}{2} = -1.5 \)
Using the standard normal table:
\( P(X \geq 125) = P(Z \geq -1.5) = 1 – P(Z < -1.5) = 1 – 0.0668 \)
\( \boxed{P(X \geq 125) = 0.9332} \)
So about 93.3% of containers from this machine will contain at least 125 fl oz.

(c)

Let \(X_{(1)} = \min(X_1, X_2, \ldots, X_{12})\) be the smallest value among 12 randomly selected containers.
For the minimum to be at least 125 fl oz, every single one of the 12 containers must contain at least 125 fl oz.
Since the containers are independent:
\( P(X_{(1)} \geq 125) = P(X_1 \geq 125) \times P(X_2 \geq 125) \times \cdots \times P(X_{12} \geq 125) \)
\( = [P(X \geq 125)]^{12} = (0.9332)^{12} \)
\( \boxed{P(X_{(1)} \geq 125) \approx 0.4362} \)
There is roughly a 43.6% chance that the smallest of 12 containers all meet the 125 fl oz threshold.
Even though each individual container has a 93.3% chance of passing, the probability that all 12 pass simultaneously drops considerably.

(d)

From the sorted list of 150 simulated minimums, we count how many are at least 125 fl oz. Scanning the table, the minimums first reach 125.00 at sample 85. From sample 85 through sample 150, that gives:
\( 150 – 85 + 1 = 66 \text{ minimums that are} \geq 125 \text{ fl oz} \)
The simulated probability estimate is therefore:
\( \hat{p} = \frac{66}{150} \approx \boxed{0.44} \)
Comparison with the theoretical value:
The theoretical probability from part (c) was \(0.4362\).
The simulation estimate of \(0.44\) is very close — the difference is only:
\( |0.44 – 0.4362| = 0.0038 \)
This is a tiny discrepancy, which is exactly what we expect from a simulation of this size.
The simulation does an excellent job of approximating the true theoretical probability, confirming that the independence-based calculation in part (c) is correct.

Question

A pharmaceutical company has developed a new drug to reduce cholesterol. A regulatory agency will recommend the new drug for use if there is convincing evidence that the mean reduction in cholesterol level after one month of use is more than 20 milligrams/deciliter (mg/dl), because a mean reduction of this magnitude would be greater than the mean reduction for the current most widely used drug.
The pharmaceutical company collected data by giving the new drug to a random sample of 50 people from the population of people with high cholesterol. The reduction in cholesterol level after one month of use was recorded for each individual in the sample, resulting in a sample mean reduction and standard deviation of 24 mg/dl and 15 mg/dl, respectively.
(a) The regulatory agency decides to use an interval estimate for the population mean reduction in cholesterol level for the new drug. Provide this 95 percent confidence interval. Be sure to interpret this interval.
(b) Because the 95 percent confidence interval includes 20, the regulatory agency is not convinced that the new drug is better than the current best-seller. The pharmaceutical company tested the following hypotheses.
\(H_0: \mu = 20\) versus \(H_a: \mu > 20\),
where \(\mu\) represents the population mean reduction in cholesterol level for the new drug.
The test procedure resulted in a \(t\)-value of 1.89 and a \(p\)-value of 0.033. Because the \(p\)-value was less than 0.05, the company believes that there is convincing evidence that the mean reduction in cholesterol level for the new drug is more than 20. Explain why the confidence interval and the hypothesis test led to different conclusions.
(c) The company would like to determine a value \(L\) that would allow them to make the following statement.
We are 95 percent confident that the true mean reduction in cholesterol level is greater than \(L\).
A statement of this form is called a one-sided confidence interval. The value of \(L\) can be found using the following formula.
\[L = \bar{x} – t^* \dfrac{s}{\sqrt{n}}\]
This has the same form as the lower endpoint of the confidence interval in part (a), but requires a different critical value, \(t^*\). What value should be used for \(t^*\)?
Recall that the sample mean reduction in cholesterol level and standard deviation are 24 mg/dl and 15 mg/dl, respectively. Compute the value of \(L\).
(d) If the regulatory agency had used the one-sided confidence interval in part (c) rather than the interval constructed in part (a), would it have reached a different conclusion? Explain.

Most-appropriate topic codes (AP Statistics):

• Topic 4.2 — Constructing a Confidence Interval for a Population Mean or Population Mean Difference (Part a)
• Topic 4.4 — Setting Up a Test for a Population Mean or Population Mean Difference (Part b)
• Topic 4.5 — Carrying Out a Test for a Population Mean or Population Mean Difference (Part b)
• Topic 4.2 — Constructing a Confidence Interval for a Population Mean or Population Mean Difference (Part c)
• Topic 4.3 — Justifying a Claim Based on a Confidence Interval for a Population Mean or Population Mean Difference (Parts c, d)
▶️ Answer/Explanation

(a)
The appropriate procedure is a one-sample \(t\)-interval for the population mean \(\mu\).
Conditions:
— The data come from a random sample of 50 people.
— \(\sigma\) is unknown; using the sample standard deviation \(s = 15\).
— \(n = 50 \geq 30\), so by the Central Limit Theorem the sampling distribution of \(\bar{x}\) is approximately normal.
Given: \(\bar{x} = 24\), \(s = 15\), \(n = 50\), and \(df = 49\). For a 95% confidence interval, \(t^* \approx 2.009\) (using \(df = 49\)).
The confidence interval formula is:
\(\bar{x} \pm t^* \cdot \dfrac{s}{\sqrt{n}}\)
\(24 \pm 2.009 \cdot \dfrac{15}{\sqrt{50}}\)
\(24 \pm 2.009 \times 2.121\)
\(24 \pm 4.262\)
\(\boxed{(19.738,\ 28.262) \text{ mg/dl}}\)
Interpretation: We are 95% confident that the true population mean reduction in cholesterol level after one month of use of the new drug is between approximately 19.7 mg/dl and 28.3 mg/dl.

(b)
The confidence interval and the hypothesis test led to different conclusions because they are based on different types of procedures that correspond to different questions being asked.
The 95% two-sided confidence interval is equivalent to a two-sided hypothesis test at \(\alpha = 0.05\). The two-sided \(p\)-value for testing \(H_0: \mu = 20\) against \(H_a: \mu \neq 20\) would be \(2 \times 0.033 = 0.066\), which exceeds \(\alpha = 0.05\) — hence the confidence interval (which captures values consistent with a two-sided test) includes 20 and fails to reject \(H_0\) at the 0.05 level.
The hypothesis test, however, is one-sided (\(H_a: \mu > 20\)) with a one-sided \(p\)-value of \(0.033 < 0.05\), which leads to rejecting \(H_0\). A one-sided test is more powerful in the direction specified and uses only one tail of the distribution. The two procedures are therefore testing different things, and it is the mismatch — using a two-sided interval to evaluate a one-sided hypothesis — that creates the apparent contradiction in conclusions.
\(\boxed{\text{Two-sided CI} \leftrightarrow \text{two-sided test (}p = 0.066 > 0.05\text{)}; \quad \text{one-sided test: }p = 0.033 < 0.05}\)

(c)
For a one-sided 95% confidence interval, we need to find \(t^*\) such that 95% of the \(t\)-distribution with \(df = 49\) lies above \(-t^*\) (i.e., only one tail of area 0.05).
This corresponds to a tail probability of \(p = 0.05\) (one tail) with \(df = 49\). From the \(t\)-table:
\(\boxed{t^* = 1.676 \quad (df = 49,\ \text{one tail}, \ \alpha = 0.05)}\)
Now compute \(L\):
\(L = \bar{x} – t^* \cdot \dfrac{s}{\sqrt{n}} = 24 – 1.676 \cdot \dfrac{15}{\sqrt{50}}\)
\(= 24 – 1.676 \times 2.121\)
\(= 24 – 3.555\)
\(\boxed{L \approx 20.4 \text{ mg/dl}}\)
Interpretation: We are 95% confident that the true mean reduction in cholesterol level after one month of use of the new drug is greater than approximately 20.4 mg/dl.

(d)
Yes, the regulatory agency would have reached a different conclusion using the one-sided confidence interval. The one-sided interval shows that the agency can be 95% confident that the true mean reduction is greater than \(L \approx 20.4\) mg/dl, which is already above the threshold of 20 mg/dl required for recommendation. Since the entire range of plausible values for \(\mu\) under the one-sided interval lies above 20, the agency would have had convincing evidence that the new drug reduces cholesterol by more than 20 mg/dl on average — and would therefore have recommended the drug for use.
\(\boxed{L \approx 20.4 > 20 \Rightarrow \text{Yes, different conclusion: agency would recommend the drug}}\)

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