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Pre AP Biology -GEN 4.2 Sexual Reproduction (Meiosis)- MCQ Exam Style Questions -New Syllabus 2025-2026

Pre AP Biology -GEN 4.2 Sexual Reproduction (Meiosis)- MCQ Exam Style Questions – New Syllabus 2025-2026

Pre AP Biology -GEN 4.2 Sexual Reproduction (Meiosis)- MCQ Exam Style Questions – Pre AP Biology – per latest Pre AP Biology Syllabus.

Pre AP Biology – MCQ Exam Style Questions- All Topics

Question

In which of these processes are angiosperms unique among living organisms?
a. flower production and double fertilization
b. flower production and coevolution
c. germination and double fertilization
d. germination and coevolution
▶️ Answer/Explanation
Detailed solution

The correct option is a.
Angiosperms are the only group of plants that produce true flowers as reproductive structures.
They undergo double fertilization, where one sperm fuses with the egg and another with the polar nuclei.
Germination is not unique to angiosperms, as gymnosperms and ferns also germinate from seeds or spores.
Coevolution occurs across many kingdoms, such as between predators and prey or hosts and parasites.
Therefore, the combination of flowers and double fertilization defines the uniqueness of angiosperms.
This process ensures the formation of both a diploid zygote ($2n$) and a triploid endosperm ($3n$).

Question

Which of these statements best describes double fertilization?
a. Two sperm simultaneously fertilize two eggs in two separate ovules.
b. One sperm fertilizes the egg, and a second sperm fertilizes the central cell.
c. Two sperm simultaneously fertilize two antipodal cells.
d. One sperm fertilizes the egg, and a second sperm fertilizes a synergid, forming endosperm.
▶️ Answer/Explanation
Detailed solution

The correct option is b.
Double fertilization is a unique process in angiosperms involving two sperm cells.
The first $1$st sperm fuses with the egg cell to form a diploid ($2n$) zygote.
The $2$nd sperm fuses with the central cell (containing two polar nuclei).
This second fusion creates a triploid ($3n$) primary endosperm nucleus.
The zygote develops into the embryo, while the endosperm provides nutrition.
Options a, c, and d are incorrect as they misidentify the target cells or outcomes.

Question

What cells are produced when the microspore of an angiosperm divides?
a. two generative cells
b. two tube cells
c. a sperm cell, a generative cell, and a tube cell
d. a generative cell and a tube cell
▶️ Answer/Explanation
Detailed solution

The correct option is d.
The microspore is the first cell of the male gametophyte generation.
It undergoes an asymmetrical mitotic division ($1$ mitosis).
This division results in a large tube cell (vegetative cell) and a smaller generative cell.
The tube cell is responsible for pollen tube growth.
The generative cell later divides to form two male gametes (sperm cells).
At the initial stage of microspore division, only two cells are formed.

Question

In angiosperms, an egg cell is produced in which structure and by which process?
a. embryo sac, by meiosis
b. embryo sac, by mitosis
c. central cell, by mitosis
d. female gametophyte, by meiosis
▶️ Answer/Explanation
Detailed solution

The correct option is b.
In angiosperms, a diploid ($2n$) megaspore mother cell undergoes meiosis to produce four haploid ($n$) megaspores.
One functional megaspore then undergoes three rounds of mitosis to form the embryo sac (the female gametophyte).
The embryo sac typically contains $8$ haploid nuclei, one of which differentiates into the egg cell.
Since the embryo sac itself is already haploid ($n$), the egg cell is produced via mitosis within this structure.
Therefore, the egg cell is located in the embryo sac and formed through the process of mitosis.

Question

Which of the following is synthesized by reverse transcriptase?
a. RNA from DNA
b. DNA from RNA
c. proteins from DNA
d. proteins from RNA
▶️ Answer/Explanation
Detailed solution

The correct option is b.
Reverse transcriptase is an enzyme that catalyzes the process of reverse transcription.
In this process, a complementary \(\text{DNA}\) (\(\text{cDNA}\)) strand is synthesized using an \(\text{RNA}\) template.
This mechanism effectively reverses the standard flow of genetic information (Transcription).
It is primarily used by retroviruses, such as \(\text{HIV}\), to integrate their genome into the host cell.
Option a refers to transcription, while c and d involve translation and gene expression.
Therefore, the enzyme specifically builds \(\text{DNA}\) from an \(\text{RNA}\) source.

Question

Suppose that you found a leafless sporophyte with a waxy cuticle to reduce water loss, and stomata for gas exchange. Which of these plants is this plant most likely?
a. a moss
b. a fern
c. a pine tree
d. an angiosperm
▶️ Answer/Explanation
Correct Option: a. a moss

Detailed solution

In bryophytes like mosses, the sporophyte is a stalk-like structure that often lacks true leaves.
The moss sporophyte consists of a foot, seta, and a capsule where spores are produced.
Despite being leafless, these sporophytes possess a waxy cuticle to prevent desiccation.
They also feature stomata on the capsule for regulated gas exchange during development.
In contrast, ferns, pine trees, and angiosperms have dominant, leafy sporophyte generations.
Therefore, a leafless sporophyte with these specific adaptations is most characteristic of a moss.

Question

Your neighbour notices moss growing between bricks on her patio. Closer examination reveals tiny brown stalks with round tops emerging from leafy shoots. Which of the following are those brown structures most likely?
a. antheridia
b. archegonia
c. a gametophyte generation
d. a sporophyte generation
▶️ Answer/Explanation
Detailed solution

Ans : d. a sporophyte generation
The tiny brown stalks with round tops are sporophytes in mosses. The leafy shoots are the gametophyte, from which the sporophyte emerges after fertilization. The round tops are spore capsules.

Explanation :
In moss life cycle, the green leafy part is the dominant haploid gametophyte.
Antheridia (a) are male gametangia producing sperm on the gametophyte.
Archegonia (b) are female gametangia producing eggs on the gametophyte.
Gametophyte generation (c) refers to the leafy base, not the emerging stalks.
Sporophyte generation (d) is the diploid phase: a stalk (seta) with a round capsule containing spores.
These brown structures match the sporophyte, which depends on the gametophyte for nutrition.
This alternation of generations is typical in bryophytes like mosses.
The description fits common moss sporophytes seen in damp areas like patios.

Question

The delivery of mature $\text{mRNA}$ to the cytoplasm in eukaryotes is highly controlled. At which one of these levels of regulation is this control achieved?
a. translational
b. posttranslational
c. transcriptional
d. posttranscriptional
▶️ Answer/Explanation
Detailed solution

The correct option is d. posttranscriptional.
In eukaryotes, transcription occurs within the nucleus to produce pre-$\text{mRNA}$.
Post-transcriptional regulation includes processing steps like capping, splicing, and polyadenylation.

The nuclear pore complex strictly regulates the export of only mature $\text{mRNA}$ to the cytoplasm.
This transport mechanism is a key checkpoint occurring after transcription but before translation.
Therefore, the control of $\text{mRNA}$ delivery is classified as post-transcriptional regulation.
Other levels like translational or post-translational occur only after the $\text{mRNA}$ has reached the cytoplasm.

Question

How does chromatin remodelling activate gene expression?
a. It allows repressors to disengage from the promoter.
b. It winds genes tightly around histones.
c. It inserts nucleosomes into chromatin.
d. It recruits a protein complex that displaces nucleosomes from the promoter.
▶️ Answer/Explanation
Detailed solution

The correct option is d.
Chromatin remodeling involves the restructuring of nucleosomes to change DNA accessibility.
Specific protein complexes use energy from $ATP$ hydrolysis to slide or eject nucleosomes.
This process clears the promoter region of the gene.
By displacing these nucleosomes, the underlying $DNA$ sequences become accessible.
This allows RNA polymerase and transcription factors to bind to the promoter.
Consequently, the initiation of transcription is triggered, thereby activating gene expression.

Question

Which of these statements accurately describes the functioning of the $trp$ operon?
a. Tryptophan is an inducer.
b. When end-product tryptophan binds to the $trp$ repressor, it stops transcription of the tryptophan biosynthesis genes.
c. $trp$ repressor is synthesized in active form.
d. Low levels of tryptophan bind to the $trp$ operator and block transcription of the tryptophan biosynthesis genes.
▶️ Answer/Explanation
Detailed solution

The correct option is b.
The $trp$ operon is a repressible system used by bacteria to synthesize tryptophan.
Tryptophan acts as a corepressor, not an inducer.
When tryptophan levels are high, it binds to the inactive $trp$ repressor protein.
This binding activates the repressor, allowing it to attach to the operator site.
Once bound, the repressor physically blocks RNA polymerase from transcribing the genes.
This feedback inhibition ensures the cell does not waste energy producing excess tryptophan.

Question

If recombination occurred in a bacterium undergoing transformation as shown in the figure, what would be the final genotype of the bacterial chromosome?
a. $Mhv$
b. $MHv$
c. $mHV$
d. $mhV$
▶️ Answer/Explanation
Detailed solution

The bacterial chromosome starts with the alleles $m$, $H$, and $V$.
The first crossover occurs between the $M/m$ and $H/h$ loci.
This switches the segment from the bacterial strand ($m$) to the transformed strand ($h$).
The second crossover occurs between the $H/h$ and $V/v$ loci.
This switches the segment back from the transformed strand ($h$) to the bacterial strand ($V$).
Tracing the resulting continuous line on the chromosome: we start with $m$, cross over to pick up $h$, and cross back to pick up $V$.
Therefore, the final genotype of the integrated bacterial chromosome is $mhV$.
Correct Option: d. $mhV$

Question

The number of human chromosomes in a cell in prophase I of meiosis is ________ and in telophase II it is ________.
a. $92; 46$
b. $46; 23$
c. $23; 23$
d. $23; 46$
▶️ Answer/Explanation
Detailed solution

The correct option is b. $46; 23$.
In prophase I, the human cell is diploid ($2n$) and contains $46$ chromosomes.
Each chromosome consists of two sister chromatids, but the count remains $46$.
Meiosis I is a reduction division that separates homologous pairs.
Meiosis II then separates sister chromatids into individual cells.
By telophase II, each resulting daughter cell is haploid ($n$).
Therefore, the final count per nucleus in telophase II is $23$ chromosomes.

Question

As a result of genetic recombination, each of the chromosomes of your family dog contains a different combination of alleles compared to those of its brothers and sisters. When did this recombination occur?
a. when the dog’s parents made gametes
b. when the dog was a newly fertilized, single-celled zygote
c. when the dog grew from a zygote to a multicellular organism
d. when the dog reached sexual maturity
▶️ Answer/Explanation
Detailed solution

The correct answer is a. when the dog’s parents made gametes.

Genetic recombination happens during meiosis in the parents.

This process shuffles alleles through crossing over and independent assortment.

As a result, each gamete (sperm or egg) gets a unique combination of alleles.

When gametes fuse to form a zygote, the offspring inherits this recombined set.

Siblings get different combinations because each fertilization involves different gametes.

Recombination does not occur in the zygote, during growth, or at maturity.

These later stages involve mitosis, which does not recombine alleles.

Question

Imagine that you are helping your younger brother with his biology homework. You notice that he has written in his notes that, “Plants are haploid and make gametes by mitosis. Animals are diploid and make gametes by meiosis.” What should your response be?
a. Yes, plants make gametes by mitosis and most animals make gametes by meiosis. However, animals and plants both have a haploid and a diploid stage of their life cycle.
b. Yes, both plants and animals make gametes. The difference is that plant gametes divide by mitosis and animal gametes do not.
c. Yes, plants are simpler organisms than animals and have fewer chromosomes in their cells.
d. Yes, plants and animals use meiosis for different purposes. Animals make gametes by meiosis and plants make zygotes.
▶️ Answer/Explanation
Detailed solution

The correct answer is a.
In plants, the alternation of generations involves both a multicellular $n$ (haploid) and $2n$ (diploid) stage.
Plants produce gametes via mitosis from the haploid gametophyte stage.
Animals are primarily diploid ($2n$) and produce gametes ($n$) directly via meiosis.
Both kingdoms utilize both stages, though the dominance of each stage varies significantly.
Meiosis in plants actually produces spores, not gametes directly.
Therefore, both organisms transition between haploid and diploid phases during their life cycles.

Question

Assume for the purpose of this question that chromosomes are condensed and visible throughout the cell cycle. Which of the cells shown below is diploid?
a. $1$ only
b. $2$ only
c. $3$ only
d. $1$ and $3$
▶️ Answer/Explanation
Detailed solution

Correct Answer: d. $1$ and $3$
In cell $1$, there are $3$ distinct types of chromosomes, each present in $2$ copies (homologous pairs), making it diploid ($2n = 6$).
In cell $2$, there are $3$ different types of chromosomes but only $1$ of each, indicating it is haploid ($n = 3$).
In cell $3$, there are $3$ types of chromosomes, each consisting of $2$ sister chromatids, but still organized in homologous pairs ($2n = 6$).
A cell is diploid if it contains two complete sets of chromosomes, regardless of whether they consist of one or two chromatids.
Cell $1$ represents a diploid cell in $G_1$ phase where chromosomes are unreplicated.
Cell $3$ represents a diploid cell in $G_2$ or Prophase where chromosomes have been replicated into sister chromatids.
Therefore, both cells $1$ and $3$ satisfy the criteria for being diploid.

Question

During Meiosis I,
A. homologous chromosomes are separated.
B. sister chromatids are separated.
C. the DNA is replicated.
D. two cells divide into four cells.
▶️ Answer/Explanation
Detailed solution

The correct option is A.
Meiosis I is known as the reductional division phase.
During Anaphase I, homologous chromosomes move toward opposite poles.
Unlike mitosis, the sister chromatids remain attached at their centromeres.
DNA replication occurs only once during the $S$ phase of interphase, before Meiosis I begins.
The separation of sister chromatids occurs later, during Meiosis II.
This process results in two haploid cells, each containing half the original chromosome count.

Question

A normal human diploid ($2N$) body cell contains how many chromosomes total?
A. $23$ chromosomes
B. $46$ chromosomes
C. $44$ chromosomes
D. $46 + XX$ chromosomes
▶️ Answer/Explanation
Detailed solution

The correct answer is B.
In humans, a diploid ($2N$) cell contains two complete sets of chromosomes.
One set of $n = 23$ is inherited from the mother and one set of $n = 23$ from the father.
Therefore, the total count is $23 + 23 = 46$ chromosomes.
These include $44$ autosomes and $2$ sex chromosomes ($XX$ or $XY$).
Option A refers to the haploid ($N$) number found in gametes.
Option D is mathematically incorrect as it suggests a total of $48$ chromosomes.

Question

Dichromacy, or colorblindness, is an $X$-linked recessive disorder. A colorblind husband and his wife who is homozygous for normal vision have a child. If they have a daughter, what is the probability that the daughter will be colorblind?
A. $0\%$
B. $25\%$
C. $50\%$
D. $100\%$
▶️ Answer/Explanation
Detailed solution

Let $X^B$ be the normal allele and $X^b$ be the recessive colorblind allele.
The colorblind husband’s genotype is $X^b Y$.
The homozygous normal wife’s genotype is $X^B X^B$.

A daughter receives one $X$ chromosome from each parent ($X^B$ from mother and $X^b$ from father).
All daughters will have the genotype $X^B X^b$, making them carriers with normal vision.
Since $0$ out of $100\%$ of daughters will express the recessive phenotype, the probability is $0\%$.
Therefore, the correct option is A.

Question

Which of the following is NOT a process that leads to a large amount of genetic variation in sexual reproducing eukaryotic organisms?
A. The random organization and separation of chromosomes during Meiosis.
B. Crossing over and the exchange of alleles during Meiosis.
C. The random combination of different egg or sperm cells during fertilization.
D. The separation of sister chromatids during Anaphase of Mitosis.
▶️ Answer/Explanation
Detailed solution

Correct Option: D
Meiosis creates variation via independent assortment and crossing over.
Fertilization increases diversity by combining unique gametes randomly.
Mitosis is a process of asexual cellular replication.
During Anaphase of Mitosis, identical sister chromatids are separated.
This results in two daughter cells that are genetically identical.
Therefore, Mitosis does not contribute to genetic variation in the population.

Question

During which of the following processes are homologous chromosomes organized and separated?
A. Mitosis
B. Meiosis I
C. Meiosis II
D. Fertilization
▶️ Answer/Explanation
Detailed solution

The correct answer is B. Meiosis I.
In Meiosis I, homologous pairs align at the metaphase plate and separate during anaphase I.
In Mitosis and Meiosis II, it is the sister chromatids that are separated, not homologous pairs.
Fertilization is the fusion of gametes, which combines chromosomes rather than separating them.
This specific separation in Meiosis I reduces the chromosome number from $2n$ to $n$.
Therefore, the organization and segregation of homologs is unique to the first division of meiosis.

Question

What is the consequence of a frameshift mutation?
(A) A single nucleotide change that does not alter the amino acid sequence.
(B) The insertion or deletion of nucleotides, resulting in a shift in the reading frame of the codons.
(C) The replacement of one nucleotide with another, resulting in a silent mutation.
(D) A mutation that occurs in somatic cells but not germ cells.
▶️ Answer/Explanation
Detailed solution

The correct answer is (B).
A frameshift mutation occurs when nucleotides are added or removed in numbers not divisible by $3$.
Since $mRNA$ is read in triplets, this alters the grouping of every subsequent codon downstream.
This typically changes every amino acid in the polypeptide chain following the mutation site.
It often results in a premature stop codon, leading to a truncated, non-functional protein.
Options (A) and (C) describe point mutations, specifically silent mutations, which do not shift the frame.
Option (D) describes the location of a mutation rather than its biochemical mechanism or consequence.

Question

In animal was cloned in a lab, producing five genetically identical offspring. The offspring were then sent to five different zoos. After five years, scientists collected data on these animals and found a variation in their heights. What is the most likely explanation for the data?
A. Each clone experienced mutations with no effect on its genes.
B. Each clone experienced a different environment with no effect on its genes.
C. Each clone experienced the same mutations, which influenced the expression of its genes.
D. Each clone experienced a different environment, which influenced the expression of its genes.
▶️ Answer/Explanation
Correct Answer: D
Detailed solution

The offspring are genetically identical because they are clones, meaning their DNA sequences are the same.
Variation in physical traits (phenotypes) like height often results from environmental factors.
Different zoos provide different diets, climates, and care, which trigger different gene expressions.
This interaction between genes and the environment is known as phenotypic plasticity.
Mutations (Options A and C) are rare and unlikely to occur identically or insignificantly across all five.
Environmental influence on gene expression (epigenetics) perfectly explains how identical DNA produces different results.

Question

Do You Play Basketball?
“Wow! You are tall. Do you play basketball?” Judd gets asked this question at least once a day. At \(6’7”\) he is very tall. Judd’s dad is tall (\(6’3”\)), and Judd’s mom is above average height for women (\(5’9”\)). How can it be that Judd is taller than both of his parents?
Human height is controlled by at least three genes, each with two alleles: dominant (\(T\)) and recessive (\(t\)), where \(T\) is expressed as tall height. Figure 1 (described below) shows how Judd’s parents’ genes for height might have resulted in Judd’s genotype for height.
Multiple genotypes for human height are possible, so there are many possible variations in phenotypes. The range of phenotypes for human height in males is shown in Figure 2.

Q. Select the choice that best completes the statement.

The cells of the embryo are     1     because of     2    .

A. 1: haploid; 2: fertilization
B. 1: diploid; 2: meiotic division
C. 1: diploid; 2: fertilization
D. 1: haploid; 2: genetic recombination

Q. Judd has a 20-year-old sister. Her height is \(5’4”\). Which statement best explains why his sister is shorter than him and their parents?

A. She received no genes for height from her mother.
B. She received no genes for height from either parent.
C. The embryo that became Judd’s sister had a higher percentage of recessive alleles than the embryo that became Judd.
D. The embryo that became Judd’s sister had a higher percentage of dominant alleles than the embryo that became Judd.

Q. Which statement best describes the trait for height, based on Figure 2?

A. Height is a sex-linked trait.
B. Height is a polygenic trait.
C. Height has no genotypic expression.
D. Height follows a simple Mendelian inheritance pattern.

Q. Some of the phenotypes for male height are identified by two distinct ranges.

  • Range 1: 50-55 inches
  • Range 2: 75-80 inches

Which choice best describes how these height ranges are represented in Figure 2?

A. Both Range 1 and Range 2 represent rare phenotypes for male height.
B. Both Range 1 and Range 2 represent common phenotypes for male height.
C. Range 1 represents a rare phenotype, while Range 2 represents a common phenotype for male height.
D. Range 1 represents a common phenotype, while Range 2 represents a rare phenotype for male height.

Q. Judd visits an exhibit at a local museum. A display there describes a recent research study where people from several distinct neighborhoods in a large U.S. city were surveyed for height. The display features the data table below.

*Evaluation of socioeconomic status includes income, social standing, education level, and occupation. Evaluation of health includes factors such as frequency of illness, nutritional status, and access to health care.

What can most likely be inferred from the research data?

A. The trait for height results from mutational changes in a person’s DNA sequence.
B. The trait for height can be influenced by the environment in which a person lives.
C. The trait for height results from genetic diversity in the neighborhood’s gene pool.
D. The trait for height is influenced by the heights of other people living in the environment.
▶️ Answer/Explanation
Detailed solution

A. (C)
Gametes (sperm and egg) are haploid cells produced by meiosis. When they fuse during the process of fertilization, they combine their genetic material to form a zygote (embryo). The resulting embryo is diploid, meaning it contains two full sets of chromosomes (one from each parent).

A. (C)
Height is a polygenic trait determined by multiple alleles (represented by \(T\) and \(t\)). Because parents are heterozygous for various genes, independent assortment during meiosis creates diverse combinations. The sister received a higher percentage of recessive “short” alleles (\(t\)) compared to Judd, resulting in a shorter phenotype.

A. (B)
Figure 2 shows a continuous bell-shaped distribution of height. Traits that show a continuous range of phenotypes (rather than distinct categories like “tall” or “short”) are typically polygenic, meaning they are controlled by the interaction of multiple genes.

A. (A)
In a normal distribution histogram (Figure 2), the height of the bars represents the frequency of the trait. The ranges 50–55 inches and 75–80 inches are located at the extreme “tails” of the graph where the bars are very short or non-existent. This indicates that both ranges represent rare phenotypes.

A. (B)
The data shows a correlation between socioeconomic status/health and average height. Neighborhood 1 (positive health/high status) has the tallest average, while Neighborhood 2 (negative health/low status) has the shortest. This suggests that environmental factors like nutrition and healthcare availability significantly influence the phenotypic expression of height.

Question

A farmer reads this information:

  • A bacterium has a gene that allows it to create pesticide.
  • The gene has been transferred into a corn plant, allowing the corn plant to produce pesticide.

Why might a farmer choose to plant genetically engineered corn?

A. to spread mutations from the corn to other crops
B. to reduce chemical use during the growing season
C. to allow the fields to be used for more than one season
D. to decrease the amount of land needed to grow the corn crop
▶️ Answer/Explanation
Correct Answer: B
Detailed solution

The correct option is B because:
Genetically engineered corn (such as Bt corn) produces its own internal pesticide.
This biological trait allows the plant to defend itself against specific insect pests naturally.
Consequently, farmers do not need to apply as many external chemical sprays to the fields.
Reducing chemical use lowers production costs and minimizes environmental runoff.
Options A, C, and D are not direct biological outcomes of producing an internal pesticide.

Question

This diagram represents the DNA fingerprint for a man, a woman, and four different babies, one of which is the man and woman’s baby.
Based on the DNA fingerprints, which is most likely the man and woman’s baby?
A. Baby W
B. Baby X
C. Baby Y
D. Baby Z
▶️ Answer/Explanation
Correct Answer: C. Baby Y
Detailed solution

In DNA fingerprinting, every band in a child’s profile must be present in at least one parent’s profile.
By comparing Baby Y to the parents, we see that its top two bands match the Woman.
The middle thick band and the next two lower bands in Baby Y match the Man’s profile.
The bottom-most band in Baby Y matches a corresponding band in the Woman’s profile.
Other babies (W, X, and Z) possess unique bands that do not appear in either the Man or the Woman.
Since all bands in Baby Y are accounted for by the potential parents, it is the biological offspring.

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