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Edexcel iGCSE Biology-3.14 B Platelets & Blood Clotting- Study Notes- New Syllabus

Edexcel iGCSE Biology-3.14 B Platelets & Blood Clotting- Study Notes- New syllabus

Edexcel iGCSE Biology-3.14 B Platelets & Blood Clotting- Study Notes -Edexcel iGCSE Biology – per latest Syllabus.

Key Concepts:

3.14B understand how platelets are involved in blood clotting, which prevents blood loss and the entry of micro-organisms

Edexcel iGCSE Biology-Concise Summary Notes- All Topics

Role of Platelets in Blood Clotting

📝 Introduction

Platelets (thrombocytes) are small cell fragments in the blood.
Their main role: prevent blood loss and stop pathogens from entering through wounds.
Blood clotting is also called coagulation.

🔑 How Platelets Work in Clotting

  • Detection of Injury
    When a blood vessel is damaged, platelets stick to the broken area.
    They release chemicals to signal more platelets.
  • Formation of Platelet Plug
    Platelets clump together at the wound → forms a temporary platelet plug.
  • Fibrin Mesh Formation
    Chemicals from platelets trigger fibrinogen → fibrin conversion.
    Fibrin threads form a mesh over the wound.
    RBCs get trapped → stable clot formed.
  • Protection Against Micro-organisms
    Clot seals the wound → prevents entry of bacteria and viruses.

🔑 Key Points

  • Platelets are cell fragments, not full cells.
  • Blood clotting is a vital defence mechanism.
  • The clot is temporary → tissue heals underneath, then clot dissolves.
  • Vitamin K and calcium ions are essential for clotting.

📊 Summary Table

StepWhat HappensRole
Platelet adhesionPlatelets stick to damaged vesselDetect injury
Platelet aggregationPlatelets clump togetherForm temporary plug
Fibrin formationFibrin mesh traps RBCsStable clot
ProtectionWound sealedPrevent blood loss & infection

⚡ Quick Recap 
Platelets → clot formation → prevents blood loss & infection.
Steps: stick → clump → fibrin mesh → stable clot.
Vitamin K & calcium → essential for clotting.

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