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Edexcel iGCSE Biology-4.22 Polygenic Inheritance- Study Notes- New Syllabus

Edexcel iGCSE Biology-4.22 Polygenic Inheritance- Study Notes- New syllabus

Edexcel iGCSE Biology-4.22 Polygenic Inheritance- Study Notes -Edexcel iGCSE Biology – per latest Syllabus.

Key Concepts:

4.22 understand that most phenotypic features are the result of polygenic inheritance rather than single genes

Edexcel iGCSE Biology-Concise Summary Notes- All Topics

Polygenic Inheritance

🧬 Introduction

Not all traits are controlled by a single gene.
Many important characteristics are influenced by multiple genes working together.
This type of inheritance is called polygenic inheritance.

📖 Key Points

  • Definition: Polygenic inheritance = when a characteristic is controlled by two or more genes (often located on different chromosomes).
  • Each gene may have two or more alleles, and their combined effect influences the phenotype.
  • Unlike single-gene traits (e.g., flower color in peas), polygenic traits show a wide range of variation (continuous variation).

🌸 Examples of Polygenic Traits in Humans

  • Height – influenced by many genes + environment (nutrition).
  • Skin color – controlled by several genes affecting melanin production.
  • Eye color – multiple genes interact to give a range of colors.
  • Weight – combination of genes + lifestyle (diet/exercise).

📊 Difference Between Single-Gene vs Polygenic Traits

FeatureSingle-Gene (Monogenic)Polygenic
Number of genesControlled by 1 geneControlled by many genes
VariationDiscrete (clear categories)Continuous (range of values)
ExamplesBlood group (A, B, AB, O)Height, skin color, eye color
GraphBar chart with distinct groupsBell-shaped curve (normal distribution)

📈 Continuous Variation in Polygenic Traits

Polygenic traits show gradual differences in phenotype.
Example: Height → ranges from very short to very tall, with many intermediate values.
If graphed, produces a bell-shaped curve (normal distribution).

📌 Quick Recap
– Polygenic inheritance = many genes control one trait.
– Produces continuous variation (smooth range, not categories).
– Examples: height, skin color, weight, eye color.
– Contrast: Monogenic inheritance → single gene, discrete categories (like blood groups).
✨ Trick: Poly = Many → Polygenic = Many genes for one trait.

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