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Edexcel iGCSE Biology-4.23 Monohybrid Inheritance: Genetic Diagrams- Study Notes- New Syllabus

Edexcel iGCSE Biology-4.23 Monohybrid Inheritance: Genetic Diagrams- Study Notes- New syllabus

Edexcel iGCSE Biology-4.23 Monohybrid Inheritance: Genetic Diagrams- Study Notes -Edexcel iGCSE Biology – per latest Syllabus.

Key Concepts:

4.23 describe patterns of monohybrid inheritance using a genetic diagram

Edexcel iGCSE Biology-Concise Summary Notes- All Topics

Monohybrid Inheritance

🌱 Introduction

Monohybrid inheritance studies how a single gene (with two alleles) is inherited.
It shows how alleles are passed from parents to offspring and how they combine to give different phenotypes.

📖 Key Concepts

  • Gene: A section of DNA controlling a trait (e.g., flower color).
  • Allele: Different versions of the same gene (e.g., R = red, r = white).
  • Homozygous: Two identical alleles (RR or rr).
  • Heterozygous: Two different alleles (Rr).
  • Dominant allele: Expressed even if only one copy is present (R).
  • Recessive allele: Only expressed if both copies are present (rr).
  • Genotype: Genetic makeup (RR, Rr, rr).
  • Phenotype: Observable trait (red or white flower).

🌸 Example: Flower Colour

Gene for flower colour → Alleles: R (red, dominant) and r (white, recessive)

1. Cross between Homozygous Red (RR) × Homozygous White (rr)

  • Parent Genotypes: RR × rr
  • Gametes: R, R × r, r
  • F1 Genotypes: All Rr
  • F1 Phenotype: All red (since R is dominant).

2. Self-Cross of F1 Generation (Rr × Rr)

  • Parent Genotypes: Rr × Rr
  • Gametes: R, r × R, r
 Rr
RRRRr
rRrrr
  • Genotype ratio: 1 RR : 2 Rr : 1 rr
  • Phenotype ratio: 3 Red : 1 White

📊 Summary Table

CrossGenotypesPhenotypes
RR × rr100% Rr100% Red
Rr × Rr1 RR : 2 Rr : 1 rr3 Red : 1 White

📌 Quick Recap
– Monohybrid inheritance = study of one gene with two alleles.
– Uses Punnett squares to predict outcomes.
– Dominant allele masks recessive.
– Classic F2 ratio (for heterozygote cross) = 3:1 phenotype.
✨ Trick: Mono = One → focus on one gene at a time.

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