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Edexcel iGCSE Biology-4.26 &4.27 Sex Chromosomes- Study Notes- New Syllabus

Edexcel iGCSE Biology-4.26 &4.27 Sex Chromosomes- Study Notes- New syllabus

Edexcel iGCSE Biology-4.26 &4.27 Sex Chromosomes- Study Notes -Edexcel iGCSE Biology – per latest Syllabus.

Key Concepts:

4.26 understand how the sex of a person is controlled by one pair of chromosomes, XX in a female and XY in a male
4.27 describe the determination of the sex of offspring at fertilisation, using a genetic diagram

Edexcel iGCSE Biology-Concise Summary Notes- All Topics

Sex Determination in Humans

🌱 Key Idea

A person’s sex is determined by one specific pair of chromosomes called sex chromosomes.
Humans have 23 pairs of chromosomes, but the 23rd pair decides male or female.

🔹 Sex Chromosome Combinations

SexChromosome PairKey Feature
FemaleXXBoth chromosomes are X → female characteristics develop
MaleXYOne X and one Y → male characteristics develop

How Sex is Determined

  • All eggs from the female carry an X chromosome.
  • Sperm from the male can carry X or Y.
  • Fertilisation determines sex:
    • X sperm + X egg → XX → Female
    • Y sperm + X egg → XY → Male
  • The male gamete decides the sex of the offspring.

Key Points

  • Sex is determined at fertilisation.
  • XX → female, XY → male.
  • Male gamete is critical because it can carry either X or Y.
  • Probability of male or female offspring = 50:50.

📌 Quick Recap
– 23rd chromosome pair = sex chromosomes.
– XX = female, XY = male.
– Male sperm determines the sex → X = girl, Y = boy.
– Probability of male/female = 1:1.
💡 Tip: “Father decides the child’s sex.”

Sex Determination at Fertilisation

🌱 Key Idea

The sex of the offspring is decided at the moment of fertilisation, depending on which sperm (X or Y) fuses with the egg.
Eggs always carry X chromosomes.
Sperm carry either X or Y chromosomes.

Genetic Principle

  • XX → Female
  • XY → Male
  • The male gamete determines the sex of the child because it can contribute either an X or Y chromosome.

Genetic Diagram

 X (Egg)
X (Sperm)XX → Female
Y (Sperm)XY → Male

Probability of Female = 50%
Probability of Male = 50%

Stepwise Explanation

  • Female produces eggs (X).
  • Male produces sperm (X or Y).
  • Fertilisation occurs when one sperm fuses with an egg.
  • Resulting zygote:
    • XX → develops into female
    • XY → develops into male

Key Points

  • Male sperm decides the sex of the offspring.
  • Probability of male or female = 1:1.
  • Can be illustrated clearly using a Punnett square.

📌 Quick Recap
– Egg = always X, Sperm = X or Y.
– XX = female, XY = male.
– Fertilisation determines sex.
– Male gamete is critical in sex determination.

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