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Edexcel International GCSE in Biology (Modular) Exam Style Questions - New Syllabus

Edexcel International GCSE in Biology (Modular) Exam Style Questions

Edexcel International GCSE in Biology (Modular) Exam Style Questions at  IITian Academy  focus on a specific topic or type of questions asked in actual exam. Notes are based on new syllabus for assessment of 2025

Concise and comprehensive Edexcel International GCSE in Biology (Modular) Exam Style Questions. Prepare for your exams effectively with our clear and concise summaries. Ace your Edexcel iGCSE Biology exams! Improve your understanding of iGCSE Biology with our expertly crafted Exam Style Questions. Identify key concepts, strengthen your knowledge, and boost your confidence. Achieve exam success with our effective study tool.

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Biology Paper 1*Paper code 4BI1/1B and 4SD0/1B
  • Externally assessed
  • Availability: November and June
  • First assessment: June 2019
61.1% of the total International GCSE

Assessment

  • The paper is assessed through a 2 hour written examination paper set and marked by Pearson.
  • The total number of marks is 110.
  • A mixture of different question styles, including multiple choice questions, short answer questions, calculations and extended open response questions.
  • A calculator may be used in the examinations.

Edexcel Biology Paper 1

Topic 1: The nature and variety of living organisms

Characteristics of living organisms

Variety of living organisms

Topic 2 : Structure and functions in living organisms

 Level of Organisation

  • 2.1 Levels of organisation

Cell Structure

  • 2.2 Describe Cell structures
  • 2.3 Functions of Nucleus 
  • 2.4 Similarities & differences: plant vs animal cells

Biological Molecules

  • 2.7 Chemical elements in carbohydrates, proteins, lipids
  • 2.8 Structure of carbs/proteins/lipids (starch & glycogen from simple sugars; proteins from amino acids; lipids from fatty acids + glycerol)
  • 2.10 Enzymes as biological catalysts
  • 2.11 Effect of temperature on enzyme function (active site changes)
  • 2.13 Effect of pH on enzyme function (active site)

 Movement of Substances In & Out of Cells

  • 2.15 Diffusion, osmosis, active transport
  • 2.16 Factors affecting movement: SA:Vol, distance, temp, concentration gradient

 Nutrition

  • Flowering plants
    • 2.18 Photosynthesis and conversion of light → chemical energy
    • 2.19 Word + balanced symbol equation
    • 2.20 Factors affecting photosynthesis
    • 2.21 Leaf structure adaptations
    • 2.22 Mineral ions: Mg for chlorophyll; nitrate for amino acids
  • Humans
    • 2.24 Components of a balanced diet
    • 2.25 Sources & functions of nutrients (A, C, D; Ca; Fe; water; fibre)
    • 2.26 Energy requirements: activity, age, pregnancy
    • 2.27 Structure/function of alimentary canal
    • 2.28 Peristalsis
    • 2.29 Digestive enzymes: amylase/maltase, proteases, lipases
    • 2.30 Bile produced in liver; stored in gallbladder
    • 2.31 Bile neutralises acid + emulsifies lipids
    • 2.32 Small intestine adaptations + villus structure

Respiration

  • 2.34 Respiration produces ATP
  • 2.35 ATP provides energy
  • 2.36 Aerobic vs anaerobic respiration
  • 2.37 Word + balanced chemical equation for aerobic respiration
  • 2.38 Word equation for anaerobic respiration in plants & animals

Gas Exchange

  • Humans
    • 2.46 Structure of thorax
    • 2.47 Diaphragm & intercostal muscles in ventilation
    • 2.48 Alveoli adaptations
    • 2.49 Biological consequences of smoking

Transport

  • General
    • 2.51 Unicellular organisms rely on diffusion
    • 2.52 Need for transport in multicellular organisms
  • Flowering plants
    • 2.53 Phloem transports sucrose & amino acids
    • 2.54 Xylem transports water & minerals
  • Humans
    • 2.59 Components of blood
    • 2.60 Role of plasma
    • 2.61 RBC adaptations
    • 2.62 Immune system: phagocytes & lymphocytes
    • 2.63B Vaccination → memory cells
    • 2.64B Platelets in blood clotting
    • 2.65 Heart structure & function
    • 2.66 Heart rate changes; adrenaline
    • 2.67 Risk factors for CHD
    • 2.68 Arteries, veins, capillaries
    • 2.69 Structure of circulation system

Excretion

  • Plants
    • 2.70 CO₂ & O₂ as waste products, lost through stomata

  • Humans
    • 2.71 Excretory products of lungs, kidneys, skin

 Coordination & Response

  • General
    • 2.80 Response to environment
    • 2.81 Homeostasis
    • 2.82 Stimulus → receptor → effector
  • Plants
    • 2.83 Plants respond to stimuli
    • 2.84 Geotropism & phototropism
    • 2.85 Auxin in phototropism
  • Humans
    • 2.86 Nervous vs hormonal control
    • 2.87 CNS = brain + spinal cord; nerves to sense organs
    • 2.88 Electrical impulses → rapid responses
    • 2.89 Neurotransmitters at synapses
    • 2.90 Reflex arc
    • 2.91 Eye structure & function
    • 2.92 Focusing + light intensity response
    • 2.93 Skin in temperature regulation
    • 2.94 Hormones: adrenaline, insulin, testosterone, progesterone, oestrogen

Topic 3 : Reproduction & Inheritance

Reproduction

  • General Reproduction Concepts
    • 3.1 Sexual vs Asexual Reproduction
    • 3.2 Fertilisation → Zygote → Embryo Development
  • Flowering Plants
    • 3.3 Insect-pollinated vs Wind-pollinated Flowers
    • 3.4 Pollen Tube Growth & Fertilisation → Seeds & Fruits
    • 3.6 Use of Food Reserves in Germinating Seeds
    • 3.7 Asexual Reproduction in Plants (Runners & Cuttings)
  • Humans
    • 3.8 Male & Female Reproductive System Adaptations
    • 3.9 Roles of Oestrogen & Progesterone
    • 3.10B Roles of FSH & LH
    • 3.11 Placenta & Nutrition of Embryo
    • 3.12 Amniotic Fluid & Embryo Protection
    • 3.13 Hormones in Secondary Sexual Characteristics

Inheritance

  • Genetic Material
    • 3.14 Genome & Gene Meaning
    • 3.15 Chromosomes & Gene Location
  • Genes & Patterns of Inheritance
    • 3.19 Alleles & Variation
    • 3.20 Dominant, Recessive, Genotype, Phenotype
    • 3.21B Codominance
    • 3.22 Polygenic Inheritance
    • 3.23 Monohybrid Inheritance (Genetic Diagram)
    • 3.24 Reading Family Pedigrees
    • 3.25 Predicting Monohybrid Cross Outcomes
  • Sex Determination
    • 3.26 XX/XY Chromosomes
    • 3.27 Sex of Offspring at Fertilisation
  • Cell Division
    • 3.28 Mitosis → Two Identical Diploid Cells
    • 3.29 Roles of Mitosis
    • 3.30 Meiosis → Four Haploid, Genetically Different Cells
    • 3.31 Random Fertilisation → Variation
  • Chromosomes & Variation
    • 3.32 Diploid (46) & Haploid (23) Numbers
    • 3.33 Genetic vs Environmental Variation
    • 3.34 Mutation (Inherited Random Change)
  • Mutations, Evolution & Antibiotic Resistance
    • 3.38 Darwin’s Natural Selection
    • 3.39 Antibiotic Resistance in Bacteria

Topic 4: Ecology & The Environment

The Organism in the Environment

    • 4.1 Population, Community, Habitat & Ecosystem
    • 4.2 Practical: Population Size Using Quadrats
    • 4.5 Abiotic & Biotic Factors Affecting Population Size

Feeding Relationships

    • 4.6 Trophic Levels
    • 4.7 Food Chains, Food Webs & Ecological Pyramids
    • 4.8 Transfer of Substances & Energy in Food Chains
    • 4.9 Why Only ~10% of Energy Passes to Next Trophic Level

Cycles Within Ecosystems

    • 4.10 Stages of the Carbon Cycle

Human Influences on the Environment

    • 4.12 Air Pollution: Sulfur Dioxide & Carbon Monoxide
    • 4.13 Greenhouse Gases 
    • 4.14 Human Activities Increasing Greenhouse Gases
    • 4.15 Enhanced Greenhouse Effect → Global Warming
    • 4.16 Water Pollution by Sewage
    • 4.17 Eutrophication from Mineral Runoff

Topic 5 : Use of Biological Resources

Food Production

  • Crop Plants
    • 5.1 Glasshouses & Polythene Tunnels for Increasing Crop Yield
    • 5.2 Effects of CO₂ & Temperature on Crop Yield
    • 5.3 How Fertilisers Increase Crop Yield
    • 5.4 Pest Control
  • Micro-organisms
    • 5.5 Role of Yeast in Bread Making
    • 5.7 Role of Bacteria in Yoghurt Production
    • 5.8 Industrial Fermenter

Selective Breeding

  • 5.10 Selective Breeding for Desired Plant Characteristics
  • 5.11 Selective Breeding for Desired Animal Characteristics

Genetic Modification (Genetic Engineering)

  • 5.12 Restriction Enzymes & Ligase Enzymes in DNA Cutting & Joining
  • 5.13 Plasmids & Viruses as Vectors for Recombinant DNA
  • 5.14 Manufacturing Human Insulin Using Genetically Modified Bacteria
  • 5.15 Genetically Modified Plants for Improving Food Production
  • 5.16 Meaning of “Transgenic”

Biology Paper 2*Paper code 4BI1/2B
  • Externally assessed
  • Availability: November and June
  • First assessment: June 2019
38.9 percent of the total International GCSE

Assessment

  • The paper is assessed through a 1 hour and 15 minute written examination paper set and marked by Pearson.
  • The total number of marks is 70.
  • A mixture of different question styles, including multiple choice questions, short answer questions, calculations and extended open response questions.
  • A calculator may be used in the examinations.

Edexcel Biology Paper 2

Topic 1: The nature and variety of living organisms

Characteristics of living organisms

  • 1.1 Characteristics of Living Organisms

Variety of living organisms

  • 1.2 Common Features of Eukaryotic Organisms
  • 1.3 Common Features of Prokaryotic Organisms
  • 1.4 Pathogens

Topic 2 : Structure and functions in living organisms

 Level of Organisation

  • 2.1 Levels of organisation

Cell Structure

  • 2.2 Describe Cell structures
  • 2.3 Functions of Nucleus 
  • 2.4 Similarities & differences: plant vs animal cells
  • 2.5B Importance of cell differentiation for specialised cells
  • 2.6B Advantages & disadvantages of using stem cells in medicine

Biological Molecules

  • 2.7 Chemical elements in carbohydrates, proteins, lipids
  • 2.8 Structure of carbs/proteins/lipids (starch & glycogen from simple sugars; proteins from amino acids; lipids from fatty acids + glycerol)
  • 2.10 Enzymes as biological catalysts
  • 2.11 Effect of temperature on enzyme function (active site changes)
  • 2.13 Effect of pH on enzyme function (active site)

 Movement of Substances In & Out of Cells

  • 2.15 Diffusion, osmosis, active transport
  • 2.16 Factors affecting movement: SA:Vol, distance, temp, concentration gradient

 Nutrition

  • Flowering plants
    • 2.18 Photosynthesis and conversion of light → chemical energy
    • 2.19 Word + balanced symbol equation
    • 2.20 Factors affecting photosynthesis
    • 2.21 Leaf structure adaptations
    • 2.22 Mineral ions: Mg for chlorophyll; nitrate for amino acids
  • Humans
    • 2.24 Components of a balanced diet
    • 2.25 Sources & functions of nutrients (A, C, D; Ca; Fe; water; fibre)
    • 2.26 Energy requirements: activity, age, pregnancy
    • 2.27 Structure/function of alimentary canal
    • 2.28 Peristalsis
    • 2.29 Digestive enzymes: amylase/maltase, proteases, lipases
    • 2.30 Bile produced in liver; stored in gallbladder
    • 2.31 Bile neutralises acid + emulsifies lipids
    • 2.32 Small intestine adaptations + villus structure

Respiration

  • 2.34 Respiration produces ATP
  • 2.35 ATP provides energy
  • 2.36 Aerobic vs anaerobic respiration
  • 2.37 Word + balanced chemical equation for aerobic respiration
  • 2.38 Word equation for anaerobic respiration in plants & animals

Gas Exchange

  • Flowering plants
    • 2.40B Diffusion in gas exchange
    • 2.41B Gas exchange in relation to photosynthesis & respiration
    • 2.42B Leaf adaptations
    • 2.43B Role of stomata
    • 2.44B Day/night respiration & net gas exchange
  • Humans
    • 2.46 Structure of thorax
    • 2.47 Diaphragm & intercostal muscles in ventilation
    • 2.48 Alveoli adaptations
    • 2.49 Biological consequences of smoking

Transport

  • General
    • 2.51 Unicellular organisms rely on diffusion
    • 2.52 Need for transport in multicellular organisms
  • Flowering plants
    • 2.53 Phloem transports sucrose & amino acids
    • 2.54 Xylem transports water & minerals
    • 2.55B Water absorption by root hair cells
    • 2.56B Transpiration = evaporation of water
    • 2.57B Factors affecting transpiration: humidity, wind, temp, light
  • Humans
    • 2.59 Components of blood
    • 2.60 Role of plasma
    • 2.61 RBC adaptations
    • 2.62 Immune system: phagocytes & lymphocytes
    • 2.63B Vaccination → memory cells
    • 2.64B Platelets in blood clotting
    • 2.65 Heart structure & function
    • 2.66 Heart rate changes; adrenaline
    • 2.67 Risk factors for CHD
    • 2.68 Arteries, veins, capillaries
    • 2.69 Structure of circulation system

Excretion

  • Plants
    • 2.70 CO₂ & O₂ as waste products, lost through stomata

  • Humans
    • 2.71 Excretory products of lungs, kidneys, skin
    • 2.72B Kidney: excretion & osmoregulation
    • 2.73B Urinary system structure
    • 2.74B Nephron structure
    • 2.75B Ultrafiltration & filtrate composition
    • 2.76B Water reabsorption from collecting duct
    • 2.77B Selective reabsorption of glucose in PCT
    • 2.78B Role of ADH
    • 2.79B Composition of urine

 Coordination & Response

  • General
    • 2.80 Response to environment
    • 2.81 Homeostasis
    • 2.82 Stimulus → receptor → effector
  • Plants
    • 2.83 Plants respond to stimuli
    • 2.84 Geotropism & phototropism
    • 2.85 Auxin in phototropism
  • Humans
    • 2.86 Nervous vs hormonal control
    • 2.87 CNS = brain + spinal cord; nerves to sense organs
    • 2.88 Electrical impulses → rapid responses
    • 2.89 Neurotransmitters at synapses
    • 2.90 Reflex arc
    • 2.91 Eye structure & function
    • 2.92 Focusing + light intensity response
    • 2.93 Skin in temperature regulation
    • 2.94 Hormones: adrenaline, insulin, testosterone, progesterone, oestrogen
    • 2.95B Hormones: ADH, FSH, LH

Topic 3 : Reproduction & Inheritance

Reproduction

  • General Reproduction Concepts
    • 3.1 Sexual vs Asexual Reproduction
    • 3.2 Fertilisation → Zygote → Embryo Development
  • Flowering Plants
    • 3.3 Insect-pollinated vs Wind-pollinated Flowers
    • 3.4 Pollen Tube Growth & Fertilisation → Seeds & Fruits
    • 3.5 Practical: Conditions for Seed Germination
    • 3.6 Use of Food Reserves in Germinating Seeds
    • 3.7 Asexual Reproduction in Plants (Runners & Cuttings)
  • Humans
    • 3.8 Male & Female Reproductive System Adaptations
    • 3.9 Roles of Oestrogen & Progesterone
    • 3.10B Roles of FSH & LH
    • 3.11 Placenta & Nutrition of Embryo
    • 3.12 Amniotic Fluid & Embryo Protection
    • 3.13 Hormones in Secondary Sexual Characteristics

Inheritance

  • Genetic Material
    • 3.14 Genome & Gene Meaning
    • 3.15 Chromosomes & Gene Location
    • 3.16B DNA Structure (Double Helix, Base Pairing)
    • 3.17B RNA Structure (Single-Strand, Uracil)
    • 3.18B Protein Synthesis: Transcription & Translation
  • Genes & Patterns of Inheritance
    • 3.19 Alleles & Variation
    • 3.20 Dominant, Recessive, Genotype, Phenotype
    • 3.21B Codominance
    • 3.22 Polygenic Inheritance
    • 3.23 Monohybrid Inheritance (Genetic Diagram)
    • 3.24 Reading Family Pedigrees
    • 3.25 Predicting Monohybrid Cross Outcomes
  • Sex Determination
    • 3.26 XX/XY Chromosomes
    • 3.27 Sex of Offspring at Fertilisation
  • Cell Division
    • 3.28 Mitosis → Two Identical Diploid Cells
    • 3.29 Roles of Mitosis
    • 3.30 Meiosis → Four Haploid, Genetically Different Cells
    • 3.31 Random Fertilisation → Variation
  • Chromosomes & Variation
    • 3.32 Diploid (46) & Haploid (23) Numbers
    • 3.33 Genetic vs Environmental Variation
    • 3.34 Mutation (Inherited Random Change)
  • Mutations, Evolution & Antibiotic Resistance
    • 3.35B DNA Changes → Protein Changes → Phenotype
    • 3.36B Most Mutations Have No Effect
    • 3.37B Mutagens: Radiation & Chemicals
    • 3.38 Darwin’s Natural Selection
    • 3.39 Antibiotic Resistance in Bacteria

Topic 4: Ecology & The Environment

The Organism in the Environment

    • 4.1 Population, Community, Habitat & Ecosystem
    • 4.2 Practical: Population Size Using Quadrats
    • 4.3B Meaning of Biodiversity
    • 4.4B Practical: Distribution of Organisms & Measuring Biodiversity
    • 4.5 Abiotic & Biotic Factors Affecting Population Size

Feeding Relationships

    • 4.6 Trophic Levels (Producers → Consumers → Decomposers)
    • 4.7 Food Chains, Food Webs & Ecological Pyramids
    • 4.8 Transfer of Substances & Energy in Food Chains
    • 4.9 Why Only ~10% of Energy Passes to Next Trophic Level

Cycles Within Ecosystems

    • 4.10 Stages of the Carbon Cycle
    • 4.11B Stages of the Nitrogen Cycle (Roles of Bacteria & Decomposers)

Human Influences on the Environment

    • 4.12 Air Pollution: Sulfur Dioxide & Carbon Monoxide
    • 4.13 Greenhouse Gases (CO₂, Methane, Nitrous Oxide, CFCs, etc.)
    • 4.14 Human Activities Increasing Greenhouse Gases
    • 4.15 Enhanced Greenhouse Effect → Global Warming
    • 4.16 Water Pollution by Sewage
    • 4.17 Eutrophication from Mineral Runoff
    • 4.18B Effects of Deforestation (Leaching, Erosion, Carbon Cycle Disruption)

Topic 5 : Use of Biological Resources

Food Production

  • Crop Plants
    • 5.1 Glasshouses & Polythene Tunnels for Increasing Crop Yield
    • 5.2 Effects of CO₂ & Temperature on Crop Yield
    • 5.3 How Fertilisers Increase Crop Yield
    • 5.4 Pest Control
  • Micro-organisms
    • 5.5 Role of Yeast in Bread Making
    • 5.7 Role of Bacteria in Yoghurt Production
    • 5.8 Industrial Fermenter
  • Fish Farming
    • 5.9B Methods for Large-Scale Fish Farming

Selective Breeding

  • 5.10 Selective Breeding for Desired Plant Characteristics
  • 5.11 Selective Breeding for Desired Animal Characteristics

Genetic Modification (Genetic Engineering)

  • 5.12 Restriction Enzymes & Ligase Enzymes in DNA Cutting & Joining
  • 5.13 Plasmids & Viruses as Vectors for Recombinant DNA
  • 5.14 Manufacturing Human Insulin Using Genetically Modified Bacteria
  • 5.15 Genetically Modified Plants for Improving Food Production
  • 5.16 Meaning of “Transgenic”

Cloning

  • 5.17B Micropropagation (Tissue Culture) & Growth of Explants In Vitro
  • 5.18B Micropropagation for Producing Genetically Identical Plants
  • 5.19B Stages of Cloning Mammals (e.g., Dolly the Sheep)
  • 5.20B Cloned Transgenic Animals for Producing Human Proteins
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