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Edexcel A Level (IAL) Biology -5.23 Mutation, Natural Selection & Evolution- Study Notes- New Syllabus

Edexcel A Level (IAL) Biology -5.23 Mutation, Natural Selection & Evolution- Study Notes- New syllabus

Edexcel A Level (IAL) Biology -5.23 Mutation, Natural Selection & Evolution- Study Notes -Edexcel A level Biology – per latest Syllabus.

Key Concepts:

  • 5.23 understand how evolution (a change in allele frequency) can come about through gene mutation and natural selection

Edexcel A level Biology-Study Notes- All Topics

Evolution Through Gene Mutation and Natural Selection

🌱 Introduction

Evolution happens when the frequency of alleles in a population changes across generations. Two main drivers of this change are:

  • Gene mutation
  • Natural selection

Together, they explain how species adapt and why populations look different over time.

🧪 Gene Mutation (the source of variation)

What is a mutation?

A mutation is a random change in DNA. It creates new alleles or alters existing ones.

Why mutations matter

  • They introduce genetic variation.
  • Without mutations, all individuals would have identical alleles and evolution could not occur.

🌿 Types of mutations (simple exam-friendly list)

  • Beneficial → increases survival or reproduction
  • Neutral → no effect
  • Harmful → decreases survival

Key idea

Mutation = new allele enters the population → gives natural selection something to act on.

🦁 Natural Selection (the sorting process)

What natural selection does

  • Individuals with advantageous alleles survive better and reproduce more.
  • These alleles get passed on more often.
  • Over generations, the population has more of the advantageous allele.

🧠 Memory Trick

Survive → Reproduce → Pass on → Increase
(How an advantageous allele becomes common)

🔄 How Mutation + Natural Selection Change Allele Frequency

  • A mutation creates a new allele.
  • If this allele is advantageous, organisms carrying it survive better.
  • These survivors produce more offspring.
  • More offspring carry the advantageous allele.
  • Over time, the frequency of this allele increases.
  • Harmful alleles become less common because individuals carrying them survive less.

This steady shift in allele proportions is evolution.

📊 Summary Table

ProcessWhat HappensResult
MutationNew alleles appear randomlyCreates variation
Natural selectionBest-adapted individuals survive and reproduceAdvantageous alleles increase
EvolutionAllele frequency changes over timePopulation becomes better adapted
🧾 Quick Recap 
✔ Mutation creates new alleles
✔ Natural selection spreads beneficial alleles
✔ Individuals with useful traits survive and reproduce
✔ Allele frequencies shift → this is evolution
✔ Harmful alleles decrease, advantageous alleles increase
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