Home / IB DP Biology- B1.1 Carbohydrates and lipids- IB Style Questions For HL Paper 2

IB DP Biology- B1.1 Carbohydrates and lipids- IB Style Questions For HL Paper 2 -FA 2025

Question

Voltage-gated ion channels are specialized membrane proteins embedded within the phospholipid bilayer. They allow ions to move rapidly across the membrane in response to changes in membrane potential. The diagram illustrates a voltage-gated potassium (\(K^+\)) channel in both its closed and open positions.
(a) Describe how a voltage-gated potassium channel functions during an action potential.
(b) Identify another form of gated ion channel.
(c) Outline the amphipathic nature of phospholipid bilayers.
(d) Summarize how cholesterol influences membrane fluidity.
(e) Summarize how different fatty acids affect membrane fluidity.

Most-appropriate topic codes (CED):

TOPIC C2.2: Neural signalling — part (a)
TOPIC B2.1: Membranes and membrane transport — parts (b), (d), (e)
TOPIC B1.1: Carbohydrates and lipids — part (c)
▶️ Answer/Explanation
Detailed solution

(a)
When a neuron depolarizes due to the entry of \(\text{Na}^+\), the change in membrane voltage triggers the voltage-gated potassium channels to open. As these channels open, \(\text{K}^+\) ions move out of the axon by diffusion. This outward flow of positive charge helps the membrane to return to a negative potential, causing repolarization and eventually contributing to the restoration of the resting potential.

(b)
An example is a ligand-gated ion channel (also known as a neurotransmitter-gated channel).

(c)
Phospholipids have both hydrophilic and hydrophobic regions. Their phosphate head groups are attracted to water (hydrophilic), while their fatty acid tails repel water (hydrophobic). This dual nature allows them to spontaneously form bilayers.

(d)
Cholesterol helps to stabilize membrane fluidity. At higher temperatures, it reduces excessive fluidity, and at lower temperatures, it prevents the membrane from becoming too rigid.

(e)
Fatty acids with unsaturated tails increase membrane fluidity because their bends (kinks) prevent tight packing. Fatty acids that are mostly saturated decrease fluidity because they pack together more tightly.

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