Home / IB DP Biology- B2.1 Membranes and membrane transport- IB Style Questions For HL Paper 2

IB DP Biology- B2.1 Membranes and membrane transport- IB Style Questions For HL Paper 2 -FA 2025

Question

The diagram shows the original cell membrane model proposed by Singer and Nicolson in 1972.

(a) Identify with the letter H the hydrophilic region of a phospholipid molecule.

(b) Describe how this membrane model differs from the Davson–Danielli model.

(c) Explain the function of molecules such as M in the operation of sodium–potassium pumps.

▶️ Answer/Explanation

(a)

The label H indicates the hydrophilic head of the phospholipid. This polar region interacts with water inside and outside the cell, while the hydrophobic fatty-acid tails orient inward, forming the bilayer structure described by the fluid mosaic model.

(b)

The Singer–Nicolson (fluid mosaic) model and the Davson–Danielli model differ in several important ways:

  • Fluid Mosaic Model:
    • Proteins are embedded within the phospholipid bilayer.
    • Membrane components can move, giving the membrane a fluid nature.
    • Includes integral proteins spanning the bilayer—not only at the surface.
  • Davson–Danielli Model:
    • Proposed a protein–lipid–protein sandwich arrangement.
    • Proteins were thought to coat both sides of the bilayer.
    • Did not account for transmembrane proteins or membrane fluidity.

Key difference: The fluid mosaic model includes mobile, embedded proteins, while the Davson–Danielli model proposed static surface proteins.

(c)

Molecules like M function as part of the sodium–potassium pump, an active transport protein. Using energy from ATP, the pump moves 3 Na⁺ ions out of the cell and 2 K⁺ ions in.

This process allows the cell to:

  • Maintain its electrical gradient (essential for nerve and muscle function)
  • Regulate osmotic balance and cell volume
  • Preserve correct ion concentrations on either side of the membrane
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