Home / IB DP Biology- C1.2 Cell respiration IB Style Questions For HL Paper 1A

IB DP Biology- C1.2 Cell respiration IB Style Questions For HL Paper 1A -FA 2025

Question

What occurs during the stages of respiration?

OptionStage of respirationDecarboxylationReduced NAD produced
AGlycolysisNoNo
BLink reactionYesNo
CKrebs cycleYesYes
DElectron transport chainNoYes
▶️ Answer/Explanation
The Krebs cycle (citric acid cycle) includes decarboxylation steps that release CO₂ and produces multiple reduced electron carriers (including NADH).
Answer: (C)

Question

Which molecules are reactants and products during glycolysis?

▶️Answer/Explanation

Answer: C

Explanation:

Glycolysis is the first step of cellular respiration, happening in the cytoplasm, where:

  • Glucose (6-carbon sugar) → gets broken down into 2 pyruvate molecules (3-carbon each).
  • ATP is used and also made.
  • NAD⁺ is reduced to NADH.

So the correct reactants & products of glycolysis are:

  • Reactants: Glucose and ATP (ATP is used in early steps).
  • Products: Pyruvate, ATP (net gain), and reduced NAD (NADH)

Let’s match this to the options in your table:

OptionReactantsProductsVerdict
APyruvate and ATPAcetyl-CoA, CO₂, NADThis is link reaction, not glycolysis.
BGlucose and oxygenPyruvate, CO₂, ATPWrong – glycolysis doesn’t need oxygen.
CGlucose and ATPPyruvate, reduced NAD, ATPCorrect
DPyruvate and oxygenATP and reduced NADSounds like aerobic respiration after glycolysis.

Question

What term is used for ATP synthesis coupled to electron transport and proton movement?

A.  Chemiosmosis

B.  Oxidation

C.  Glycolysis

D.  Cell respiration

▶️Answer/Explanation

Answer: A. Chemiosmosis

Explanation:

What is chemiosmosis?
Chemiosmosis is the process where a flow of protons (H⁺ ions) across a membrane drives the formation of ATP. This happens in the mitochondria during oxidative phosphorylation part of aerobic respiration.

A. Correct – This is the definition of chemiosmosis: ATP synthesis driven by a proton gradient.
B. Incorrect – Oxidation is the loss of electrons, not the full process of ATP generation.
C. Incorrect – Glycolysis is the earlier step in respiration, not linked directly to the ETC or ATP synthase.
D. Incorrect – Cell respiration is the entire process, not the specific mechanism.

Question

Where are protons pumped, to allow chemiosmosis in aerobic respiration to occur?

A. From outside the mitochondrion through the double membranes

B. From carrier to carrier in the inner mitochondrial membrane

C. From the matrix of the mitochondrion to the space between the membranes

D. From the space between the membranes to the cytoplasm outside the mitochondrion

▶️Answer/Explanation

Answer: C. From the matrix of the mitochondrion to the space between the membranes

Explanation:

Proton pumping in mitochondria
During electron transport, protons (H⁺) are pumped from the matrix into the intermembrane space of the mitochondrion. This builds up a proton gradient, and the flow of protons back into the matrix through ATP synthase generates ATP.

A. Incorrect – Protons move across the inner membrane, not both membranes, and they stay inside the mitochondrion.
B. Incorrect – Protons are not passed from carrier to carrier; electrons are.
C. Correct – Protons are pumped from the matrix to the space between the membranes (intermembrane space), creating the gradient.
D. Incorrect – Protons do not go to the cytoplasm; they stay within mitochondrial compartments.

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