Home / IB DP Biology- C3.2 Defense against disease – IB Style Questions For SL Paper 1A

IB DP Biology- C3.2 Defense against disease - IB Style Questions For SL Paper 1A -FA 2025

Question

Which type of cell belongs to the innate (non-specific) immune system?

A. Phagocytes
B. B-lymphocytes
C. T-lymphocytes
D. Helper T-cells

▶️ Answer/Explanation
The innate immune system gives a rapid, non-specific response. Phagocytes (such as macrophages and neutrophils) engulf and digest pathogens immediately, so they are part of innate immunity. B-lymphocytes, T-lymphocytes, and helper T-cells are part of the adaptive immune system.
Answer: (A) Phagocytes

Question

What property of antibiotics makes them effective in the treatment of infectious diseases?

A. They stimulate the production of antibodies.
B. They block metabolic pathways in prokaryotes.
C. They block the metabolic processes in viruses.
D. They inhibit mitosis in eukaryotes.

▶️ Answer/Explanation

Antibiotic action diagram Answer: (B) They block metabolic pathways in prokaryotes.

Explanation:
Antibiotics are effective because they selectively target metabolic pathways or cell structures that exist in prokaryotic cells (bacteria) but not in human cells. Examples include:
• Inhibiting bacterial cell wall synthesis
• Blocking bacterial ribosomes to stop protein synthesis

These differences allow antibiotics to kill or stop bacteria without harming human cells.

Option Evaluation:
A. Incorrect — Antibody production is done by the immune system, not antibiotics.
B. Correct — Antibiotics target pathways unique to bacteria.
C. Incorrect — Viruses lack their own metabolic pathways, so antibiotics cannot affect them.
D. Incorrect — Antibiotics do not inhibit mitosis in eukaryotes; that would damage human cells.

Answer: (B)

 

Question

The diagram shows the major events involved in the formation of a blood clot.

Blood clotting diagram

What is Factor Y?

A. Fibrin
B. Prothrombin
C. Fibrinogen
D. Thrombin

▶️ Answer/Explanation

Answer: (D) Thrombin

Explanation:
The diagram represents the blood clotting cascade, in which several clotting factors activate one another in sequence, leading to the formation of a fibrin clot.

Key steps:

• Tissue damage releases clotting factors from platelets and damaged cells.
• These activate an enzymatic cascade involving multiple clotting factors.
• Upstream factors (often labelled W and X) help convert prothrombin into thrombin.
Factor Y is thrombin, the active enzyme that converts fibrinogen (Factor Z) into fibrin, forming the clot mesh.

Matching each option:

OptionSubstanceRoleLabel
AFibrinForms clot meshFactor Z
BProthrombinInactive precursor of thrombinPrecursor to Y
CFibrinogenConverted into fibrinNot Y
DThrombinConverts fibrinogen to fibrinFactor Y

Answer: (D) Thrombin

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