Home / iGCSE Biology (0610)-17.1 Chromosomes, genes and proteins – iGCSE Style Questions Paper 2

iGCSE Biology (0610)-17.1 Chromosomes, genes and proteins – iGCSE Style Questions Paper 2

Question

Which of the statements about the production of a protein are correct?

  1. The sequence of bases in the gene determines the amino acid sequence used to make a protein.
  2. The mRNA molecules are made in the nucleus and they remain there.
  3. The ribosomes assemble amino acids together to make a protein.

A) 1 and 2 only
B) 1 and 3 only
C) 2 and 3 only
D) 2 only

▶️ Answer/Explanation
Solution

Ans: B

Statement 1 is correct: The DNA base sequence in a gene directly codes for the amino acid sequence of a protein through transcription and translation.

Statement 2 is incorrect: mRNA is synthesized in the nucleus but leaves to travel to ribosomes in the cytoplasm for translation.

Statement 3 is correct: Ribosomes are the cellular machinery that assemble amino acids into polypeptide chains during translation.

Since only statements 1 and 3 are correct, the answer is B (1 and 3 only).

Question

The diagram shows the bases in a section of DNA from one strand only.

A−C−T−T−C−A−G−T−C

What is the base sequence on the complementary DNA strand?

A) G−C−T−T−C−G−A−T−C
B) G−T−C−C−T−G−A−C−T
C) T−C−A−A−C−T−G−A−C
D) T−G−A−A−G−T−C−A−G

▶️ Answer/Explanation
Solution

Ans: D

In DNA, base pairing follows specific rules: A (Adenine) pairs with T (Thymine), and C (Cytosine) pairs with G (Guanine). Given the strand A−C−T−T−C−A−G−T−C, the complementary strand is derived by pairing each base accordingly:

A → T, C → G, T → A, T → A, C → G, A → T, G → C, T → A, C → G

Thus, the complementary sequence is T−G−A−A−G−T−C−A−G, which matches option D.

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