CIE iGCSE Co-Ordinated Science B12. Respiration Exam Style Questions Paper 3
Question


Most-appropriate topic codes (Cambridge IGCSE Coordinated Sciences 0654):
• Topic B11.1 — Gas exchange in humans (Part (a)(i), (a)(ii), (b)(i))
• Topic B12.1 — Respiration (Part (a)(iii), (a)(iv))
• Topic B16.3 — Monohybrid inheritance (Part (b)(ii), (b)(iii))
▶️ Answer/Explanation
(a)(i) P – rib; Q – alveolus / alveoli
The ribs (P) protect the lungs and move during breathing. Alveoli (Q) are tiny air sacs where gas exchange occurs between air and blood.
(a)(ii) Diaphragm labelled D
The diaphragm is a dome-shaped muscle at the base of the chest cavity that contracts and relaxes to change the volume of the thorax during breathing.
(a)(iii) oxygen
Aerobic respiration requires oxygen as the final electron acceptor in the electron transport chain, allowing complete breakdown of glucose to carbon dioxide and water.
(a)(iv) Any two from: muscle contraction; protein synthesis; cell division; growth; the passage of nerve impulses; the maintenance of a constant body temperature
Energy from respiration is used for many cellular processes including mechanical work, biosynthesis, and maintaining homeostasis.
(b)(i) trachea / bronchi
Ciliated cells line the airways (trachea and bronchi). Their cilia beat to move mucus upwards, removing trapped particles and pathogens.
(b)(ii) Father’s genotype: Ff; Offspring genotypes: FF, Ff, Ff, ff
Both parents must be carriers (Ff) to have a child with cystic fibrosis (ff). The Punnett square shows a 1 in 4 chance of the child inheriting two recessive alleles.

(b)(iii) heterozygous and has two different alleles
The mother’s genotype is Ff, meaning she has one dominant allele (F) and one recessive allele (f), which is the definition of heterozygous.
Question

Most-appropriate topic codes (Cambridge IGCSE Co-ordinated Sciences 0654):
• Topic B2.1 — Cell structure (Part (a)(i))
• Topic B2.1 — Cell structure (Part (a)(ii))
• Topic B12.1 — Respiration (Part (b))
• Topic B3.2 — Osmosis (Part (c))
• Topic B2.1 — Cell structure (Part (d))
▶️ Answer/Explanation
(a)(i) cell membrane, cytoplasm, mitochondria, nucleus
These structures are found in both plant and animal cells. Chloroplasts, cell walls and large vacuoles are present only in plant cells.
(a)(ii) Cytoplasm: site of metabolic/chemical reactions ; Cell wall: protects/supports the cell
The cytoplasm is where most cellular reactions occur. The cell wall provides structural support and protection, maintaining the shape of the cell.
(b)(i) glucose + oxygen → carbon dioxide + water
Aerobic respiration uses glucose and oxygen to release energy, producing carbon dioxide and water as waste products.
(b)(ii) Protein synthesis / cell division / growth / muscle contraction / passage of nerve impulses / maintenance of constant body temperature / active transport
Energy from respiration is used for many essential life processes including growth, movement and active transport across cell membranes.
(c) Water moves into the potato tissue ; mass increases ; osmosis
Pure water has a higher water potential than the potato cells. Water moves into the potato cells by osmosis through the partially permeable cell membrane, causing the mass to increase.
(d) Plant leaves are thin, flat organs made up of tissues including phloem and epidermis.
Leaves are organs composed of different tissues such as epidermal tissue and vascular tissue (phloem and xylem).
