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CIE iGCSE Co-ordinated Sciences-B13.2 Hormones - Study Notes- New Syllabus

CIE iGCSE Co-ordinated Sciences-B13.2 Hormones – Study Notes

CIE iGCSE Co-ordinated Sciences-B13.2 Hormones – Study Notes -CIE iGCSE Co-ordinated Sciences – per latest Syllabus.

Key Concepts:

Core

  • Describe a hormone as a chemical substance, produced by a gland and carried by the blood, which alters the activity of one or more specific target organs
  • Identify in diagrams and images specific endocrine glands and state the hormones they secrete, limited to:
    (a) adrenal glands and adrenaline
    (b) pancreas and insulin
    (c) testes and testosterone
    (d) ovaries and oestrogen
  • Describe adrenaline as the hormone secreted in ‘fight or flight’ situations and its effects, limited to:
    (a) increased breathing rate
    (b) increased heart rate
    (c) increased pupil diameter

Supplement

  • State that glucagon is secreted by the pancreas

CIE iGCSE Co-Ordinated Sciences-Concise Summary Notes- All Topics

Hormones

📌 Definition

A hormone is a chemical substance, produced by a gland, carried in the blood, which alters the activity of one or more specific target organs.

🌱 Key Features of Hormones

  • Made by endocrine glands (e.g. pancreas, adrenal, pituitary).
  • Travel in the bloodstream (not along nerves).
  • Each hormone affects only its specific target organ(s).
  • Cause slower but longer-lasting effects compared to nerve impulses.

📊 Examples

HormoneGlandTarget organEffect
InsulinPancreasLiver, musclesLowers blood glucose
AdrenalineAdrenal glandHeart, musclesPrepares body for “fight or flight”
TestosteroneTestesMale reproductive systemControls development of male features
OestrogenOvariesFemale reproductive systemControls menstrual cycle, female features

⚡ Quick Recap
Hormone = chemical messenger.
Made in glands → carried in blood → affects target organ.
Works slower than nerves but lasts longer.
Memory tip: “Hormones hurry through blood to organs.”

Endocrine Glands and Their Hormones

📌 Introduction

Endocrine glands release hormones directly into the blood. These hormones act on specific target organs to control body functions.

🌱 Key Endocrine Glands

(a) Adrenal glands

  • Location: On top of the kidneys.
  • Hormone: Adrenaline.
  • Role: Prepares body for “fight or flight” – increases heart rate, breathing rate, and glucose release.

(b) Pancreas

  • Location: Below the stomach.
  • Hormone: Insulin.
  • Role: Lowers blood glucose by converting glucose into glycogen in the liver and muscles.

(c) Testes (in males)

  • Hormone: Testosterone.
  • Role: Controls development of male secondary sexual characteristics (voice deepening, muscle growth, hair growth) and sperm production.

(d) Ovaries (in females)

  • Hormone: Oestrogen.
  • Role: Controls development of female secondary sexual characteristics and regulates the menstrual cycle.

📊 Summary Table

Endocrine glandHormoneMain effect
Adrenal glandsAdrenalinePrepares body for fight/flight
PancreasInsulinLowers blood glucose
TestesTestosteroneMale sexual development & sperm production
OvariesOestrogenFemale sexual development & menstrual cycle

⚡ Quick Recap
Adrenal → Adrenaline → fight/flight
Pancreas → Insulin → lowers glucose
Testes → Testosterone → male features
Ovaries → Oestrogen → female features & cycle
Memory tip: “APTO” = Adrenal, Pancreas, Testes, Ovaries.

Adrenaline – The “Fight or Flight” Hormone

📌 Introduction

Adrenaline is a hormone secreted by the adrenal glands (on top of the kidneys) during stressful, exciting, or emergency (‘fight or flight’) situations. It prepares the body for rapid action.

🌱 Key Effects of Adrenaline

(a) Increased breathing rate

Allows more oxygen to enter the blood.
Supplies muscles with extra oxygen for respiration → more energy for action.

(b) Increased heart rate

Pumps blood faster.
Delivers oxygen and glucose more quickly to muscles.
Removes carbon dioxide faster.

(c) Increased pupil diameter

Pupils widen (dilate).
Allows more light into the eyes → improves vision, especially in dim conditions.

📊 Summary Table

EffectPurpose in “fight or flight”
↑ Breathing rateMore oxygen into blood
↑ Heart rateFaster delivery of O₂ + glucose to muscles
↑ Pupil diameterBetter vision to detect danger

⚡ Quick Recap
Adrenaline = emergency hormone.
Triggered in fight or flight.
Key effects: breathing ↑, heart rate ↑, pupils widen.
Memory tip: “Adrenaline = Air (breathing), Blood (heart), Eyes (pupil).”

Glucagon

📌 Definition

Glucagon is a hormone secreted by the pancreas.

🌱 Key Points

  • Made in the pancreas (by special cells called alpha cells in the islets of Langerhans).
  • Works as the opposite of insulin.
  • Function: Raises blood glucose by stimulating the liver to convert stored glycogen → glucose, which is released into the blood.

📊 Glucagon vs Insulin

HormoneSecreted byEffect on blood glucose
InsulinPancreas (beta cells)Lowers glucose (stores it as glycogen)
GlucagonPancreas (alpha cells)Raises glucose (breaks down glycogen)

⚡ Quick Recap
Glucagon = pancreas hormone.
Role = increase blood sugar.
Opposite to insulin.
Memory tip: “Glucagon is gone? → glucose comes on!”

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