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CIE iGCSE Co-ordinated Sciences-B16.2 Cell division- Study Notes- New Syllabus

CIE iGCSE Co-ordinated Sciences-Cell division – Study Notes

CIE iGCSE Co-ordinated Sciences-Cell division – Study Notes -CIE iGCSE Co-ordinated Sciences – per latest Syllabus.

Key Concepts:

Core
 Describe mitosis as nuclear division giving rise to genetically identical cells (details of the stages of mitosis are not required)
 State the role of mitosis in growth, repair of damaged tissues, replacement of cells and asexual reproduction
 State that the exact replication of chromosomes occurs before mitosis
 State that during mitosis, the copies of chromosomes separate, maintaining the chromosome number in each daughter cell
 State that meiosis is involved in the production of gametes

Supplement
 Describe meiosis as reduction division in which the chromosome number is halved from diploid to haploid resulting in genetically different cells (details of the stages of meiosis are not required)

CIE iGCSE Co-Ordinated Sciences-Concise Summary Notes- All Topics

Mitosis

📌 What it is

Mitosis = nuclear division that produces genetically identical cells.

Ensures same chromosome number is maintained in daughter cells.

🌱 Why it happens

  • Growth → organism gets bigger.
  • Repair → fixes damaged tissues.
  • Replacement → old or worn-out cells are replaced.

🌸 Key Points

  • 1 parent cell → 2 daughter cells.
  • Daughter cells are genetically identical to parent.
  • Each daughter cell is diploid (2n).
  • Stages not required, just know the outcome.

📊 Quick Table

FeatureDetails
TypeNuclear division
Outcome2 daughter cells
Genetic similarityIdentical to parent
Chromosome numberSame as parent (diploid)
FunctionsGrowth, repair, replacement

⚡ Quick Recap 
Mitosis = 1 cell → 2 identical cells
Maintains chromosome number → diploid
Memory trick: “Mitosis clones cells for growth and repair.”

Role of Mitosis

📌 Introduction

Mitosis is nuclear division producing genetically identical cells.

Its main roles are in growth, repair, replacement, and asexual reproduction.

🌱 Key Roles

  • Growth
    Produces new cells → organism increases in size.
  • Repair of damaged tissues
    Replaces injured or damaged cells to restore tissue function.
  • Replacement of cells
    Replaces worn-out or dead cells (e.g., skin cells, blood cells).
  • Asexual reproduction
    Produces offspring genetically identical to the parent (e.g., in plants like strawberries, or unicellular organisms like amoeba).

📊 Summary Table

RoleDescriptionExample
GrowthProduces new cells for size increaseGrowing body tissues
RepairReplaces damaged cellsSkin after a cut
ReplacementReplaces worn-out cellsRed blood cells, skin cells
Asexual reproductionProduces identical offspringAmoeba, budding in Hydra

⚡ Quick Recap
Mitosis = clones cells → growth, repair, replacement, asexual reproduction
Memory tip: “Grow, repair, replace, reproduce → Due to mitosis!”

Chromosome Replication before Mitosis

📌 Key Statement

Before mitosis, the exact replication of chromosomes occurs.

🌱 Key Points

  • Replication ensures each daughter cell receives an identical set of chromosomes.
  • Occurs during the S-phase of interphase (before the cell actually divides).
  • Each chromosome forms two identical sister chromatids, joined at the centromere.

📊 Summary Table

FeatureDescription
TimingBefore mitosis (S-phase of interphase)
PurposeEnsure daughter cells are genetically identical
OutcomeChromosomes have sister chromatids ready for division

⚡ Quick Recap
Replication = copy chromosomes → mitosis → identical daughter cells
Memory tip: “Copy first, divide next → identical cells!”

Chromosome Separation in Mitosis

📌 Key Statement

During mitosis, the copies of chromosomes (sister chromatids) separate, ensuring each daughter cell has the same chromosome number as the parent.

🌱 Key Points

  • Each sister chromatid moves to opposite ends of the cell.
  • Ensures genetic identity of daughter cells.
  • Maintains the diploid chromosome number (2n) in each cell.

📊 Summary Table

FeatureDescription
ProcessSeparation of sister chromatids
OutcomeEach daughter cell receives identical chromosomes
Chromosome numberMaintained (diploid)

⚡ Quick Recap
Mitosis = copies separate → identical daughter cells
Memory tip: “Split the copies, keep the number same.”

Meiosis

📌 Key Statement

Meiosis is a type of cell division involved in the production of gametes (sperm and egg).

🌱 Key Points

  • Produces haploid cells (n) → one set of chromosomes.
  • Ensures that chromosome number is maintained from generation to generation after fertilisation.
  • Results in genetic variation among gametes.

📊 Summary Table

FeatureDescription
FunctionProduction of gametes
Chromosome numberHaploid (n)
OutcomeGenetic variation in gametes

⚡ Quick Recap 
Meiosis = makes gametes with half chromosomes
Memory tip: “Gametes need half → meiosis does the math!”

Meiosis

📌 Introduction

Meiosis is a type of cell division that produces gametes (sperm and egg) for sexual reproduction. It ensures the chromosome number is halved and introduces genetic variation.

🌱 Key Features of Meiosis

  • Reduction Division: Chromosome number is halved: diploid (2n) → haploid (n). Each gamete has one set of chromosomes.
  • Genetic Variation: Daughter cells are genetically different from each other and the parent. This increases variation in offspring, important for evolution and survival.
  • Production of Gametes: Occurs in sex organs: testes in males, ovaries in females. Ensures correct chromosome number is restored after fertilisation.

📊 Summary Table

FeatureDescription
Type of divisionReduction division
Chromosome numberDiploid → Haploid
Number of cells produced4 genetically different gametes
FunctionSexual reproduction, genetic variation

⚡ Quick Recap
Meiosis = 2n → n → 4 different gametes
Key points: halving chromosomes + genetic variation + gamete formation
Memory tip: “Halve the chromosomes, mix the genes, make gametes unique.”

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